Title :

Osmo-inelastic response of the intervertebral disc

Author(s) :

Derrouiche, Amil [Auteur]
Zaouali, Ameni [Auteur]
Zairi, Fahmi [Auteur]
Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515
Ismail, Jewan [Auteur]
Chaabane, Makram [Auteur]
Qu, Zhengwei [Auteur]
Zairi, Fahed [Auteur]

Journal title :

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine

Abbreviated title :

Proc. Inst. Mech. Eng. Part H-J. Eng. Med.

Volume number :

233

Pages :

332-341

Publication date :

2019-03-01

ISSN :

0954-4119

Keyword(s) :

mechanical loading state
Intervertebral disc
chemo-mechanical coupling
inelastic effects
osmo-inelastic mechanisms

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The intervertebral disc exhibits a complex inelastic response characterized by relaxation, hysteresis during cyclic loading and rate dependency. All these inelastic phenomena depend on osmotic interactions between disc ...
Show more >The intervertebral disc exhibits a complex inelastic response characterized by relaxation, hysteresis during cyclic loading and rate dependency. All these inelastic phenomena depend on osmotic interactions between disc tissues and their surrounding chemical environment. Coupling between osmotic and inelastic effects is not fully understood, so this article aimed to study the influence of chemical conditions on the inelastic behaviour of the intervertebral disc in response to different modes of loading. A total of 18 non-frozen 'motion segments' (two vertebrae and the intervening soft tissues) were dissected from the cervical spines of mature sheep. The motion segments were loaded in tension, compression and torsion at various loading rates and saline concentrations. Analysis of variance showed that saline concentration significantly influenced inelastic effects in tension and especially in compression (p < 0.05), but not in torsion. Opposite effects were seen in tension and compression. An interpretation of the underlying osmo-inelastic mechanisms is proposed in which two sources of inelastic effects are identified, that is, extracellular matrix rearrangements and fluid exchange created by osmosis.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

IMT Lille Douai
INSERM
Institut Catholique Lille
Univ. Artois
Université de Lille

Collections :

• Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515
• Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Submission date :

2022-06-15T13:58:45Z