Title :

Effects of gallic acid on the nanocrystalline hydroxyapatite formation using the neutralization process

Author(s) :

Jerdioui, S. [Auteur]
Laboratoire de Chimie Appliquée et Environnement | Laboratory of Applied and Environmental Chemistry [Université Mohammed Premier Oujda] [LCAE]
Elansari, L.L. [Auteur]
Laboratoire de Chimie Appliquée et Environnement | Laboratory of Applied and Environmental Chemistry [Université Mohammed Premier Oujda] [LCAE]
Jaradat, Nidal [Auteur]
An-Najah National University
Jodeh, S. [Auteur]
An-Najah National University
Azzaoui, K. [Auteur]
Laboratoire de Chimie Appliquée et Environnement | Laboratory of Applied and Environmental Chemistry [Université Mohammed Premier Oujda] [LCAE]
Hammouti, B. [Auteur]
Laboratoire de Chimie Appliquée et Environnement | Laboratory of Applied and Environmental Chemistry [Université Mohammed Premier Oujda] [LCAE]
Lakrat, M. [Auteur]
Laboratoire de Chimie Appliquée et Environnement | Laboratory of Applied and Environmental Chemistry [Université Mohammed Premier Oujda] [LCAE]
Tahani, A. [Auteur]
Laboratoire de Chimie Appliquée et Environnement | Laboratory of Applied and Environmental Chemistry [Université Mohammed Premier Oujda] [LCAE]
Jama, charafeddine [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Bentiss, Fouad [Auteur]
Université Chouaib Doukkali [UCD]

Journal title :

Journal of Trace Elements and Minerals

Pages :

100009

Publisher :

Elsevier BV

Publication date :

2022-12

ISSN :

2773-0506

English keyword(s) :

Hydroxyapatite nanoparticles
Gallic Acid
Adsorption-desorption isotherms
XPS surface analysis
Bone tissue regeneration

HAL domain(s) :

Chimie/Matériaux
Chimie/Polymères

English abstract : [en]

Background Hydroxyapatite nanoparticles (nHAp) have excellent properties, such as biocompatibility and osteoconductivity, which are critical for bone reconstruction. However, they remain inactive against pathogenic bacteria ...
Show more >Background Hydroxyapatite nanoparticles (nHAp) have excellent properties, such as biocompatibility and osteoconductivity, which are critical for bone reconstruction. However, they remain inactive against pathogenic bacteria that can grow in defected bone tissue, and their use in some patients may result in some undesirable inflammatory reactions. Gallic acid (GA) is known for its specific anti-inflammatory and antibacterial properties. Coupling these characteristics with nHAp is of great interest. Methods The present study investigated the preparation of nHAp in the presence of various proportions of GA (0, 0.6, 2.5, and 5 mMol) using the neutralization method at room temperature. The effect of GA on the crystallinity, chemical composition, and surface specific area (SSA) of the prepared nHAp-GA composites was also studied. Results X-ray diffraction and Brunauer-Emmett-Teller (BET) analysis revealed that the precipitation of nHAp in the presence of a low fraction of GA induced the formation of nHAp with low crystallinity and high SSA (142 m2/g), while GA at high concentration limited nHAp growth and favored the ACP formation with low SSA (32 m2/g). X-ray photoelectron spectroscopy (XPS) indicated that GA is adsorbed on the nHAp surface and controlled its growth. Conclusion Overall, the prepared nHAp/Ga composites presented chemical and structural characteristics close to those of natural bone that make them a good candidate for bone tissue regeneration.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CNRS
INRAE
ENSCL

Collections :

• Unité Matériaux et Transformations (UMET) - UMR 8207

Research team(s) :

Procédés de Recyclage et de Fonctionnalisation (PReF)

Submission date :

2022-10-03T14:35:24Z
2022-10-03T15:08:08Z