Aortic dissection: incidence, mortality ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Aortic dissection: incidence, mortality and management in France between 2012 and 2018 in the national database.
Auteur(s) :
Lejot, A. [Auteur]
Guery, A. [Auteur]
Ledieu, G. [Auteur]
Karthikesalingam, A. [Auteur]
Sobocinski, Jonathan [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Guery, A. [Auteur]
Ledieu, G. [Auteur]
Karthikesalingam, A. [Auteur]
Sobocinski, Jonathan [Auteur]

Advanced Drug Delivery Systems (ADDS) - U1008
Titre de la revue :
Annals of Vascular Surgery
Numéro :
68
Pagination :
109
Date de publication :
2021-02-04
ISSN :
1615-5947
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Background: To evaluate results of the invasive repair in the management of acute aortic dissection (AoD) in France.
Methods: Patients admitted to hospital with acute AoD from 2012 to 2018 were identified. Patient ...
Lire la suite >Background: To evaluate results of the invasive repair in the management of acute aortic dissection (AoD) in France. Methods: Patients admitted to hospital with acute AoD from 2012 to 2018 were identified. Patient demographics, severity score at admission, treatment strategy and in-hospital mortality were described. For patients undergoing intervention, perioperative complications rate was reported. A secondary analysis evaluating patients' outcome as regards of the annual caseload per center was conducted. Results: Overall, 14,706 patients with acute AoD were identified (male 64%, mean age 67, median modified Elixhauser score 5). The overall incidence increased during the study period (from 3.8 in 2012 to 4.4/100,000 in 2018) associated with a North-South gradient (respectively 3.6 vs. 4.7/100,000) and a winter peak; 45.5% (N.=6697) of patients received medical treatment alone. Among those with invasive repair, 6276 (78.3%) were defined as type A AoD (TAAD), whereas type B AoD (TBAD) accounted for 1733 patients (21.7%), of whom 1632 (94%) had TEVAR and 101 (6%) had other arterial procedures; 30-day mortality was respectively 18.9% in TAAD and 9.5% for TBAD. In high-volume centers (i.e. >20 AoD/year), a lower 3-month mortality of 22.3% was noted compared to 31.4% in the low-volume centres (P<0.001); 47% of patients reported ≥1 early major complication. TEVAR exhibited less complication (P<0.001) compared to other arterial reconstructions in TBAD.Lire moins >
Lire la suite >Background: To evaluate results of the invasive repair in the management of acute aortic dissection (AoD) in France. Methods: Patients admitted to hospital with acute AoD from 2012 to 2018 were identified. Patient demographics, severity score at admission, treatment strategy and in-hospital mortality were described. For patients undergoing intervention, perioperative complications rate was reported. A secondary analysis evaluating patients' outcome as regards of the annual caseload per center was conducted. Results: Overall, 14,706 patients with acute AoD were identified (male 64%, mean age 67, median modified Elixhauser score 5). The overall incidence increased during the study period (from 3.8 in 2012 to 4.4/100,000 in 2018) associated with a North-South gradient (respectively 3.6 vs. 4.7/100,000) and a winter peak; 45.5% (N.=6697) of patients received medical treatment alone. Among those with invasive repair, 6276 (78.3%) were defined as type A AoD (TAAD), whereas type B AoD (TBAD) accounted for 1733 patients (21.7%), of whom 1632 (94%) had TEVAR and 101 (6%) had other arterial procedures; 30-day mortality was respectively 18.9% in TAAD and 9.5% for TBAD. In high-volume centers (i.e. >20 AoD/year), a lower 3-month mortality of 22.3% was noted compared to 31.4% in the low-volume centres (P<0.001); 47% of patients reported ≥1 early major complication. TEVAR exhibited less complication (P<0.001) compared to other arterial reconstructions in TBAD.Lire moins >
Audience :
Non spécifiée
Établissement(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Collections :
Date de dépôt :
2022-12-08T01:31:12Z
2023-09-01T13:33:12Z
2023-09-01T13:33:12Z