Titre :

Antimicrobial effect and physical properties of an injectable \"active oxygen\" gel for the treatment of periodontitis.

Auteur(s) :

Sy, Kadiatou [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Flamme, Joséphine [Auteur]
Maquet, Héloïse [Auteur]
Chai, Feng [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Nuet, Christel [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Siepmann, Florence [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Agossa, Kevimy [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]

Titre de la revue :

Journal- American College of Dentists

Nom court de la revue :

Am J Dent

Numéro :

33

Pagination :

305-309

Date de publication :

2021-01-14

ISSN :

0894-8275

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Purpose: To evaluate an injectable gel, recently proposed for the controlled release of "active oxygen" in periodontal pockets, compared to an antibiotic or an antiseptic gel, respectively. Methods: The antimicrobial ...
Lire la suite >Purpose: To evaluate an injectable gel, recently proposed for the controlled release of "active oxygen" in periodontal pockets, compared to an antibiotic or an antiseptic gel, respectively. Methods: The antimicrobial activity, injectability, texture properties, swelling and water uptake of the gels were studied. Results: The "active oxygen" gel showed a bactericidal effect comparable to the two commercially available drug products (containing minocycline or chlorhexidine) on anaerobic periodontal pathogens and did not seem to affect aerobic strains. The gel was easy to inject and stable in an aqueous medium for several days. Texture analysis revealed potential gel fragility. Clinical significance: The investigated gel for local delivery of oxygen can help to selectively eradicate anaerobic bacteria associated with periodontitis and promote the recovery of a healthy-compatible oral flora.Lire moins >

Langue :

Anglais

Audience :

Internationale

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008

Date de dépôt :

2022-12-08T01:31:46Z
2023-02-22T10:38:34Z
2023-02-23T08:05:01Z