Title :

Autonomic, Immune, Metabolic, and Neuroendocrine Dimensions of Anorexia Nervosa: An Integrative View

Author(s) :

De Zorzi, Lucas [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Ranfaing, Stephane [Auteur]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Sequeira, Henrique [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Viltart, Odile [Auteur]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm - Paris Descartes]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Ranfaing, Stephane [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193

Book title :

Neuroendocrine-Immune System Interactions

Pages :

343-378

Publisher :

Springer

Publication date :

2023-03-04

ISBN :

978-3-031-21358-8

English keyword(s) :

Anorexia nervosa
Autonomic nervous system
Heart rate variability
Skin conductance
Cytokines
Ghrelin
Leptin
Cortisol

HAL domain(s) :

Sciences cognitives

English abstract : [en]

Anorexia nervosa (AN) is the psychiatric disorder with the highest mortality rate, whose etiology remains largely unknown. It mainly concerns women and is characterized notably by a voluntary food restriction leading to a ...
Show more >Anorexia nervosa (AN) is the psychiatric disorder with the highest mortality rate, whose etiology remains largely unknown. It mainly concerns women and is characterized notably by a voluntary food restriction leading to a state of undernutrition often associated with excessive physical activity. Despite specialized care, relapse is common and affects approximately 40% of patients. AN is comorbid with several other psychiatric diseases such as depression, anxiety, or compulsivity. Patients suffering from AN also present autonomic, immune, metabolic, and neuroendocrine alterations that participate in the worsening of the disease. We describe here how the autonomic and hormonal systems, main contributors to the brain-body homeostasis, participate directly or indirectly in the modulation of the immune system in AN. The complexity of the interactions between these processes reflects the complexity of AN. The understanding of such complexity could help adjust procedures to personalize medical approaches, integrating the diversity of factors leading to AN manifestations.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CNRS
CHU Lille

Collections :

• Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193

Research team(s) :

Équipe Dynamique Émotionnelle et Pathologies (DEEP)

Submission date :

2023-05-17T13:40:04Z
2023-05-31T15:16:43Z
2024-01-10T18:07:16Z