Diffusion Controlled Drug Delivery Systems
Document type :
Partie d'ouvrage: Chapitre
Permalink :
Title :
Diffusion Controlled Drug Delivery Systems
Author(s) :
Siepmann, Juergen [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Siegel, Ronald A. [Auteur]
Siepmann, Florence [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Advanced Drug Delivery Systems (ADDS) - U1008
Siegel, Ronald A. [Auteur]
Siepmann, Florence [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Scientific editor(s) :
Siepmann, Juergen
Siegel, Ronald A.
Rathbone, Michael J.
Siegel, Ronald A.
Rathbone, Michael J.
Book title :
Fundamentals and Applications of Controlled Release Drug Delivery
Volume number :
-
Issue number :
Advances in Delivery Science and Technology
Pages :
127-152
Publisher :
Springer Link
Publication place :
New York
NY
NY
Publication date :
2019-04-06
ISBN :
978-1-4614-0881-9
ISSN :
2192-6204
English keyword(s) :
Drug Release
Apparent Diffusion Coefficient
Graft Copolymer
Drug Solubility
Fluorescence Recovery After Photobleaching
Apparent Diffusion Coefficient
Graft Copolymer
Drug Solubility
Fluorescence Recovery After Photobleaching
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
This chapter presents an overview on the different types of drug delivery systems that are predominantly governed by diffusion. The systems are classified according to their physical structure (reservoir devices versus ...
Show more >This chapter presents an overview on the different types of drug delivery systems that are predominantly governed by diffusion. The systems are classified according to their physical structure (reservoir devices versus monolithic systems), as well as according to the ratio of “initial drug loading and drug solubility.” For various cases, mathematical models are briefly presented considering different device geometries. These theories are mechanistically realistic and enable quantitative description of the resulting release kinetics. Effects of formulation parameters on drug release can also be predicted quantitatively. Practical examples are given to illustrate the applicability of the presented theories and the benefits of understanding how a diffusion-controlled drug delivery system works.Show less >
Show more >This chapter presents an overview on the different types of drug delivery systems that are predominantly governed by diffusion. The systems are classified according to their physical structure (reservoir devices versus monolithic systems), as well as according to the ratio of “initial drug loading and drug solubility.” For various cases, mathematical models are briefly presented considering different device geometries. These theories are mechanistically realistic and enable quantitative description of the resulting release kinetics. Effects of formulation parameters on drug release can also be predicted quantitatively. Practical examples are given to illustrate the applicability of the presented theories and the benefits of understanding how a diffusion-controlled drug delivery system works.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Collections :
Submission date :
2023-05-30T09:53:36Z
2024-02-23T10:19:34Z
2024-02-23T10:19:34Z