Title :

Diffusion Controlled Drug Delivery Systems

Author(s) :

Siepmann, Juergen [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Siegel, Ronald A. [Auteur]

Siepmann, Florence [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008

Scientific editor(s) :

Siepmann, Juergen
Siegel, Ronald A.
Rathbone, Michael J.

Book title :

Fundamentals and Applications of Controlled Release Drug Delivery

Volume number :

-

Issue number :

Advances in Delivery Science and Technology

Pages :

127-152

Publisher :

Springer Link

Publication place :

New York
NY

Publication date :

2019-04-06

ISBN :

978-1-4614-0881-9

ISSN :

2192-6204

English keyword(s) :

Drug Release
Apparent Diffusion Coefficient
Graft Copolymer
Drug Solubility
Fluorescence Recovery After Photobleaching

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

This chapter presents an overview on the different types of drug delivery systems that are predominantly governed by diffusion. The systems are classified according to their physical structure (reservoir devices versus ...
Show more >This chapter presents an overview on the different types of drug delivery systems that are predominantly governed by diffusion. The systems are classified according to their physical structure (reservoir devices versus monolithic systems), as well as according to the ratio of “initial drug loading and drug solubility.” For various cases, mathematical models are briefly presented considering different device geometries. These theories are mechanistically realistic and enable quantitative description of the resulting release kinetics. Effects of formulation parameters on drug release can also be predicted quantitatively. Practical examples are given to illustrate the applicability of the presented theories and the benefits of understanding how a diffusion-controlled drug delivery system works.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008

Submission date :

2023-05-30T09:53:36Z
2024-02-23T10:19:34Z