Title :

[Review] Graphene-based field-effect transistors for biosensing: where is the field heading to?

Author(s) :

Szunerits, Sabine [Auteur correspondant]
NANomatériaux pour la Santé, l’Energie et l’Environnement [NANSEE - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Rodrigues, Teresa [Auteur]
NANomatériaux pour la Santé, l’Energie et l’Environnement [NANSEE - IEMN]
Austrian Institute of Technology [Vienna] [AIT]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Bagale, Rupali [Auteur]
Carbon - IEMN [CARBON - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Happy, Henri [Auteur]
Carbon - IEMN [CARBON - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Boukherroub, Rabah [Auteur]
NANomatériaux pour la Santé, l’Energie et l’Environnement [NANSEE - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Knoll, Wolfgang [Auteur]
Danube University Krems

Journal title :

Analytical and Bioanalytical Chemistry
Topical collection Advances in (Bio-)Analytical Chemistry: Reviews and Trends Collection 2024

Pages :

2137-2150

Publisher :

Springer Verlag

Publication date :

2024

ISSN :

1618-2642

English keyword(s) :

Graphene
Field-efect transistor
Bioreceptors
Sensing

HAL domain(s) :

Physique [physics]
Sciences de l'ingénieur [physics]

English abstract : [en]

Two-dimensional (2D) materials hold great promise for future applications, notably their use as biosensing channels in the field-effect transistor (FET) configuration. On the road to implementing one of the most widely ...
Show more >Two-dimensional (2D) materials hold great promise for future applications, notably their use as biosensing channels in the field-effect transistor (FET) configuration. On the road to implementing one of the most widely used 2D materials, graphene, in FETs for biosensing, key issues such as operation conditions, sensitivity, selectivity, reportability, and economic viability have to be considered and addressed correctly. As the detection of bioreceptor-analyte binding events using a graphene-based FET (gFET) biosensor transducer is due to either graphene doping and/or electrostatic gating effects with resulting modulation of the electrical transistor characteristics, the gFET configuration as well as the surface ligands to be used have an important influence on the sensor performance. While the use of back-gating still grabs attention among the sensor community, top-gated and liquid-gated versions have started to dominate this area. The latest efforts on gFET designs for the sensing of nucleic acids, proteins and virus particles in different biofluids are presented herewith, highlighting the strategies presently engaged around gFET design and choosing the right bioreceptor for relevant biomarkers.Show less >

Language :

Anglais

Popular science :

Non

ANR Project :

Pansements Actifs intégrant des Capteurs Électroniques embarqués graphène pour la Détection In-Situ De l'Infection et le Suivi de la Cicatrisation

Collections :

• Institut d'Électronique, de Microélectronique et de Nanotechnologie (IEMN) - UMR 8520

Source :

Harvested from HAL