Analytical documentation of an Arabian ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Analytical documentation of an Arabian horse fatality related to Oenanthe crocata poisoning
Auteur(s) :
Gish, Alexandr [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Robveille, Cynthia [Auteur]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Gicquel, Thomas [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
Allorge, Delphine [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Gault, Gilbert [Auteur]
Ecole Nationale Vétérinaire de Lyon [ENVL]
Gaulier, Jean-Michel [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Robveille, Cynthia [Auteur]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Gicquel, Thomas [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
Allorge, Delphine [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Gault, Gilbert [Auteur]
Ecole Nationale Vétérinaire de Lyon [ENVL]
Gaulier, Jean-Michel [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Titre de la revue :
Toxicon
Numéro :
210
Pagination :
39-43
Éditeur :
Elsevier
Date de publication :
2022-02-18
ISSN :
0041-0101
Mot(s)-clé(s) en anglais :
Oenanthe crocata poisoning
Horse
Oenanthotoxin
2,3-dihydro-oenanthotoxin
LC-HRMS
LC-DAD
Horse
Oenanthotoxin
2,3-dihydro-oenanthotoxin
LC-HRMS
LC-DAD
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Analytical detection of Oenanthe crocata toxins in biological samples is challenging because of their instability, the lack of commercially available standards and the exceptionally low detection of these molecules using ...
Lire la suite >Analytical detection of Oenanthe crocata toxins in biological samples is challenging because of their instability, the lack of commercially available standards and the exceptionally low detection of these molecules using mass spectrometry. This work aims to report the used analytical methods that allowed identification of the main plant toxins in biological samples from an equid (an Arabian horse) fatality related to hemlock water dropwort (Oenanthe crocata Linnaeus) intake. Using both LC-DAD and LC-HRMS methods allowed identification (i) of oenanthotoxin in roots found on the site, root fragments found in the stomach, stomach content, kidney, and liver, and (ii) of the hydrogenated metabolite of oenanthotoxin (2,3-dihydro-oenanthotoxin) in roots found on the site, root fragments found in the stomach, stomach content, kidney, liver and spleen. Reported analytical data about Oenanthe crocata toxins can be useful for identification of the ingested plant and for supporting a poisoning diagnosis in such cases.Lire moins >
Lire la suite >Analytical detection of Oenanthe crocata toxins in biological samples is challenging because of their instability, the lack of commercially available standards and the exceptionally low detection of these molecules using mass spectrometry. This work aims to report the used analytical methods that allowed identification of the main plant toxins in biological samples from an equid (an Arabian horse) fatality related to hemlock water dropwort (Oenanthe crocata Linnaeus) intake. Using both LC-DAD and LC-HRMS methods allowed identification (i) of oenanthotoxin in roots found on the site, root fragments found in the stomach, stomach content, kidney, and liver, and (ii) of the hydrogenated metabolite of oenanthotoxin (2,3-dihydro-oenanthotoxin) in roots found on the site, root fragments found in the stomach, stomach content, kidney, liver and spleen. Reported analytical data about Oenanthe crocata toxins can be useful for identification of the ingested plant and for supporting a poisoning diagnosis in such cases.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
Institut Pasteur de Lille
CHU Lille
Institut Pasteur de Lille
Date de dépôt :
2023-10-20T06:09:50Z
2024-02-23T10:07:43Z
2024-02-23T10:07:43Z
Fichiers
- Gish et al.pdf
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