Titre :

Human airway epithelial cells express a functional IL-5 receptor.

Auteur(s) :

Barretto, Karina T [Auteur]
University of Wisconsin School of Medicine and Public Health
Brockman-Schneider, Rebecca A [Auteur]
University of Wisconsin School of Medicine and Public Health
Kuipers, Ine [Auteur]
University of Wisconsin School of Medicine and Public Health
Basnet, Sarmila [Auteur]
University of Wisconsin School of Medicine and Public Health
Bochkov, Yury A [Auteur]
University of Wisconsin School of Medicine and Public Health
Altman, Matthew C [Auteur]
University of Washington [Seattle]
Benaroya Research Institute [Seattle] [BRI]
Jarjour, Nizar N [Auteur]
University of Wisconsin School of Medicine and Public Health
Gern, James E [Auteur]
University of Wisconsin-Madison
Esnault, Stéphane [Auteur]
University of Wisconsin School of Medicine and Public Health

Titre de la revue :

Allergy

Nom court de la revue :

Allergy

Numéro :

75

Pagination :

2127-2130

Éditeur :

Wiley

Date de publication :

2020-04-01

Statut de l’article :

Publié

ISSN :

1398-9995

Mot(s)-clé(s) en anglais :

Bronchi
Cells, Cultured
Epithelial Cells
Humans
Interleukin-13
Receptors, Interleukin-5
IL-5 receptor
RNA-sequencing
airway epithelial cells
gene expression
intracellular signaling

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

We found that HBEC expressed the IL-5 receptor, which triggered intracellular signaling and changed gene expression. This data indicate that in addition to targeting eosinophils, IL-5 and anti-IL-5 biologics may have a ...
Lire la suite >We found that HBEC expressed the IL-5 receptor, which triggered intracellular signaling and changed gene expression. This data indicate that in addition to targeting eosinophils, IL-5 and anti-IL-5 biologics may have a direct role on AEC.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Autres travaux scientifiques

Date de dépôt :

2023-10-21T11:42:41Z
2024-05-23T12:46:42Z