Title :

Consensus survey on the management of children with chemotherapy-induced febrile neutropenia and at low risk of severe infection.

Author(s) :

Givone, Aude [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Duval Destin, Jean [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Delebarre, Mathilde [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Abou-Chahla, Wadih [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Lervat, Cyril [Auteur]
Centre Régional de Lutte contre le Cancer Oscar Lambret [Lille] [UNICANCER/Lille]
Dubos, Francois [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Journal title :

Pediatric Hematology-Oncology

Abbreviated title :

Pediatr Hematol Oncol

Pages :

1-7

Publication date :

2023-06-13

ISSN :

1521-0669

English keyword(s) :

risk management
febrile neutropenia
consensus
children
Cancer

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Our aim was to identify national consensus criteria for the management of children with chemotherapy-induced febrile neutropenia (FN), for evidence-based step-down treatment approaches for patients classified at low risk ...
Show more >Our aim was to identify national consensus criteria for the management of children with chemotherapy-induced febrile neutropenia (FN), for evidence-based step-down treatment approaches for patients classified at low risk of severe infection. In 2018, a five-section, 38-item survey was e-mailed to all pediatric hematology and oncology units in France (n = 30). The five sections contained statements on possible consensus criteria for the (i) definition of FN, (ii) initial management of children with FN, (iii) conditions required for initiating step-down therapy in low-risk patients, (iv) management strategy for low-risk patients, and (v) antibiotic treatment on discharge. Consensus was defined by respondents’ combined answers (somewhat agree and strongly agree) at 75% or more. Sixty-five physicians (participation rate: 58%), all specialists in pediatric onco-hematology, from 18 centers completed the questionnaire. A consensus was reached on 22 of the 38 statements, including the definition of FN, the criteria for step-down therapy in low-risk children, and the initial care of these patients. There was no consensus on the type and duration of antibiotic therapy on discharge. In conclusion, a consensus has been reached on the criteria for initiating evidence-based step-down treatment of children with FN and a low risk of severe infection but not for the step-down antimicrobial regimen.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2023-11-15T01:49:04Z
2024-04-11T08:45:11Z