Diagnostics in Waldenström's macroglobulinemia: ...
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Article dans une revue scientifique: Article original
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Title :
Diagnostics in Waldenström's macroglobulinemia: a consensus statement of the European Consortium for Waldenström's Macroglobulinemia.
Author(s) :
Dogliotti, I. [Auteur]
Jiménez, C. [Auteur]
Varettoni, M. [Auteur]
Talaulikar, D. [Auteur]
Bagratuni, T. [Auteur]
Ferrante, M. [Auteur]
Pérez, J. [Auteur]
Drandi, D. [Auteur]
Puig, N. [Auteur]
Gilestro, M. [Auteur]
García-Álvarez, M. [Auteur]
Owen, R. [Auteur]
Jurczak, W. [Auteur]
Tedeschi, A. [Auteur]
Leblond, Veronique [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Kastritis, E. [Auteur]
Kersten, M. J. [Auteur]
D'sa, S. [Auteur]
Kaščák, M. [Auteur]
Willenbacher, W. [Auteur]
Roccaro, A. M. [Auteur]
Poulain, Stéphanie [Auteur]
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Morel, Pierre [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Kyriakou, C. [Auteur]
Fend, F. [Auteur]
Vos, J. M. I. [Auteur]
Dimopoulos, M. A. [Auteur]
Buske, C. [Auteur]
Ferrero, S. [Auteur]
García-Sanz, R. [Auteur]
Jiménez, C. [Auteur]
Varettoni, M. [Auteur]
Talaulikar, D. [Auteur]
Bagratuni, T. [Auteur]
Ferrante, M. [Auteur]
Pérez, J. [Auteur]
Drandi, D. [Auteur]
Puig, N. [Auteur]
Gilestro, M. [Auteur]
García-Álvarez, M. [Auteur]
Owen, R. [Auteur]
Jurczak, W. [Auteur]
Tedeschi, A. [Auteur]
Leblond, Veronique [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Kastritis, E. [Auteur]
Kersten, M. J. [Auteur]
D'sa, S. [Auteur]
Kaščák, M. [Auteur]
Willenbacher, W. [Auteur]
Roccaro, A. M. [Auteur]
Poulain, Stéphanie [Auteur]

Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Morel, Pierre [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Kyriakou, C. [Auteur]
Fend, F. [Auteur]
Vos, J. M. I. [Auteur]
Dimopoulos, M. A. [Auteur]
Buske, C. [Auteur]
Ferrero, S. [Auteur]
García-Sanz, R. [Auteur]
Journal title :
Leukemia
Abbreviated title :
Leukemia
Volume number :
37
Pages :
388–395
Publication date :
2022-11-27
ISSN :
1476-5551
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
The diagnosis of Waldenström’s macroglobulinemia (WM), an IgM-associated lymphoplasmacytic lymphoma, can be challenging due to the different forms of disease presentation. Furthermore, in recent years, WM has witnessed ...
Show more >The diagnosis of Waldenström’s macroglobulinemia (WM), an IgM-associated lymphoplasmacytic lymphoma, can be challenging due to the different forms of disease presentation. Furthermore, in recent years, WM has witnessed remarkable progress on the diagnostic front, as well as a deeper understanding of the disease biology, which has affected clinical practice. This, together with the increasing variety of tools and techniques available, makes it necessary to have a practical guidance for clinicians to perform the initial evaluation of patients with WM. In this paper, we present the consensus recommendations and laboratory requirements for the diagnosis of WM developed by the European Consortium of Waldenström’s Macroglobulinemia (ECWM), for both clinical practice as well as the research/academical setting. We provide the procedures for multiparametric flow cytometry, fluorescence in situ hybridization and molecular tests, and with this offer guidance for a standardized diagnostic work-up and methodological workflow of patients with IgM monoclonal gammopathy of uncertain significance, asymptomatic and symptomatic WM.Show less >
Show more >The diagnosis of Waldenström’s macroglobulinemia (WM), an IgM-associated lymphoplasmacytic lymphoma, can be challenging due to the different forms of disease presentation. Furthermore, in recent years, WM has witnessed remarkable progress on the diagnostic front, as well as a deeper understanding of the disease biology, which has affected clinical practice. This, together with the increasing variety of tools and techniques available, makes it necessary to have a practical guidance for clinicians to perform the initial evaluation of patients with WM. In this paper, we present the consensus recommendations and laboratory requirements for the diagnosis of WM developed by the European Consortium of Waldenström’s Macroglobulinemia (ECWM), for both clinical practice as well as the research/academical setting. We provide the procedures for multiparametric flow cytometry, fluorescence in situ hybridization and molecular tests, and with this offer guidance for a standardized diagnostic work-up and methodological workflow of patients with IgM monoclonal gammopathy of uncertain significance, asymptomatic and symptomatic WM.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
Submission date :
2023-11-15T02:57:49Z
2024-04-26T08:24:13Z
2024-04-26T08:24:13Z
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