Institut de Recherche Translationnelle sur l'Inflammation (INFINITE)

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http://www.lille-inflammation-research.org/fr/

Tutelles

Université de Lille
CHU Lille
Inserm

Texte de présentation

INFINITE est une unité de recherche translationnelle dédiée à l'inflammation, de niveau international. Son objectif : comprendre les mécanismes de l'inflammation et mettre au point de nouvelles solutions diagnostiques et thérapeutiques. Pour renforcer l'interdisciplinarité et la transversalité, INFINITE rassemble 110 chercheurs regroupés dans une unité de recherche construite sur des questions scientifiques organisées en 4 workpackages interconnectés.

Dépôts récents

Young Adult Patients With Paediatric-Onset Inflammatory Bowel Disease Have a Higher Educational Level and a Higher Employment Rate Than the General Population.

Sarter, H.; Le Coniac, M.; Leroyer, Ariane; et al.
United European Gastroenterol J, 22-02-2025

Article dans une revue scientifique
Characterization of the Active Enantiomer and Mapping of the Stereospecific Intermolecular Pattern of a Reference P2X7 Allosteric Antagonist

Mcgown, Andrew; Renault, Nicolas; Barczyk, Amélie; et al.
ACS Pharmacology & Translational Science, ACS Publications, 22-01-2025, 8 (2), 446-459

Article dans une revue scientifique
LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode.

Mazhari Dorooee, Darius; Ravez, Severine; Vertommen, Didier; et al.
Angewandte Chemie International Edition, Wiley-VCH Verlag, 28-02-2025, e202500518

Article dans une revue scientifiquetexte intégral
Diagnosis, Characteristics, and Outcome of Selective Anti-polysaccharide Antibody Deficiencies In A Retrospective Cohort of 55 Adult Patients.

Perrard, N.; Stabler, S.; Sanges, S.; et al.
J Clin Immunol, 22-03-2025, 45, 82

Article dans une revue scientifique
Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach.

Vergoten, Gerard; Bailly, Christian
Journal of Biomolecular Structure and Dynamics, Taylor & Francis Online, 22-04-2021, 40 (18), 8197-8205

Article dans une revue scientifique
Mechanistic insights into dimethyl cardamonin-mediated pharmacological effects: A double control of the AMPK-HMGB1 signaling axis.

Bailly, Christian; Vergoten, Gerard
Life Sciences, Elsevier, 24-10-2020, 263, 118601

Article dans une revue scientifique
N-glycosylation of High Mobility Group Box 1 protein (HMGB1) modulates the interaction with glycyrrhizin: A molecular modeling study.

Vergoten, Gerard; Bailly, Christian
Computational Biology and Chemistry, Elsevier, 11-10-2020, 88, 107312

Article dans une revue scientifique
Proposed mechanisms for the extracellular release of PD-L1 by the anticancer saponin platycodin D.

Bailly, Christian; Vergoten, Gerard
International Immunopharmacology, Elsevier, 13-08-2020, 85, 106675

Article dans une revue scientifique
Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

Bailly, Christian; Vergoten, Gerard
Pharmacology and Therapeutics, Elsevier, 04-10-2020, 214, 107618

Article dans une revue scientifique
Interaction of Norsecurinine-Type Oligomeric Alkaloids with α-Tubulin: A Molecular Docking Study

Vergoten, Gerard; Bailly, Christian
Plants-Basel, MDPI, 11-02-2025, 13 (9), 1269

Article dans une revue scientifiquetexte intégral

Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Site web

Tutelles

Texte de présentation

Dépôts récents

Young Adult Patients With Paediatric-Onset Inflammatory Bowel Disease Have a Higher Educational Level and a Higher Employment Rate Than the General Population. ﻿

Characterization of the Active Enantiomer and Mapping of the Stereospecific Intermolecular Pattern of a Reference P2X7 Allosteric Antagonist ﻿

LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode. ﻿

Diagnosis, Characteristics, and Outcome of Selective Anti-polysaccharide Antibody Deficiencies In A Retrospective Cohort of 55 Adult Patients. ﻿

Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach. ﻿

Mechanistic insights into dimethyl cardamonin-mediated pharmacological effects: A double control of the AMPK-HMGB1 signaling axis. ﻿

N-glycosylation of High Mobility Group Box 1 protein (HMGB1) modulates the interaction with glycyrrhizin: A molecular modeling study. ﻿

Proposed mechanisms for the extracellular release of PD-L1 by the anticancer saponin platycodin D. ﻿

Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome? ﻿

Interaction of Norsecurinine-Type Oligomeric Alkaloids with α-Tubulin: A Molecular Docking Study ﻿

Young Adult Patients With Paediatric-Onset Inflammatory Bowel Disease Have a Higher Educational Level and a Higher Employment Rate Than the General Population.

Characterization of the Active Enantiomer and Mapping of the Stereospecific Intermolecular Pattern of a Reference P2X7 Allosteric Antagonist

LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode.

Diagnosis, Characteristics, and Outcome of Selective Anti-polysaccharide Antibody Deficiencies In A Retrospective Cohort of 55 Adult Patients.

Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach.

Mechanistic insights into dimethyl cardamonin-mediated pharmacological effects: A double control of the AMPK-HMGB1 signaling axis.

N-glycosylation of High Mobility Group Box 1 protein (HMGB1) modulates the interaction with glycyrrhizin: A molecular modeling study.

Proposed mechanisms for the extracellular release of PD-L1 by the anticancer saponin platycodin D.

Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

Interaction of Norsecurinine-Type Oligomeric Alkaloids with α-Tubulin: A Molecular Docking Study