Title :

David Procedure: A 21-Year Experience with 300 Patients.

Author(s) :

Soquet, Jerome [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Mugnier, Agnès [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Rousse, Natacha [Auteur]

Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Juthier, Francis [Auteur]
Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Banfi, Carlo [Auteur]
Università degli Studi di Milano = University of Milan [UNIMI]
Université de Genève = University of Geneva [UNIGE]
Loobuyck, Valentin [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Coisne, Augustin [Auteur]
Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Richardson, Marjorie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Marechaux, Sylvestre [Auteur]
Groupement des Hôpitaux de l'Institut Catholique de Lille [GHICL]
Moussa, Mouhamed Djahoum [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Robin, Emmanuel [Auteur]
Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Pinçon, Claire [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Prat, Alain [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Vincentelli, Andre [Auteur]
Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011
Institut Coeur Poumon [CHU Lille]

Journal title :

Annals of Thoracic Surgery

Abbreviated title :

Ann Thorac Surg

Publication date :

2022-06-02

ISSN :

1552-6259

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background Valve-sparing aortic root replacement with the David procedure is an alternative to the Bentall procedure in patients with aortic root aneurysm. The aim of this study was to describe our long-term experience ...
Show more >Background Valve-sparing aortic root replacement with the David procedure is an alternative to the Bentall procedure in patients with aortic root aneurysm. The aim of this study was to describe our long-term experience with this technique and the predictive factors of late failure. Methods Between January 1998 and August 2019, 300 consecutive patients underwent a David procedure. Clinical and echocardiographic early- and long-term outcomes were analyzed. Median follow-up was 7.0 years (range, 4.1-11.5), with 98.3% complete. Results Early mortality was 1%. No early valve-related reoperations occurred. There were 9 cardiac-related deaths and 22 reinterventions (19 valve-related). All patients survived reoperation. In 3 patients reintervention consisted of transcatheter aortic valve implantation. Overall survival rates were 95.3% (95% confidence interval [CI], 92.0-97.2), 91.1% (95% CI, 86.5-94.2), and 82.9% (95% CI, 75.3-88.4) at 5, 10, and 15 years, respectively. Freedom from postoperative aortic insufficiency (AI) grade ≥ 2 was 84.8% (95% CI, 79.9-88.6) and 74.3% (95% CI, 67.4-79.9) at 5 and 10 years, respectively. Freedom from reintervention for aortic valve disease was 97.1% (95% CI, 94.2-98.5), 92.9% (95% CI, 88.2-95.7), and 92.5% (95% CI, 87.1-95.7) at 5, 10, and 15 years, respectively. Preoperative AI ≥ 2 (hazard ratio, 1.782; 95% CI, 1.352-2.350) and a ventriculoaortic junction ≥ 29 mm (hazard ratio, 3.379; 95% CI, 1.726-6.616) were predictive factors for postoperative AI ≥ 2 in a multivariate analysis (P < .001). Conclusions Preoperative AI ≥ 2 and a ventriculoaortic junction ≥ 29 mm were identified as risk factors for late postoperative AI ≥ 2.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2023-11-15T04:01:14Z
2024-01-16T12:37:46Z