Title :

Semen Cryopreservation in Adolescents and Young Adults with Hematologic Diseases: from Bed to Benchside

Author(s) :

Beauvais, David [Auteur]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Berthaut, I. [Auteur]
Cabannes-Hamy, A. [Auteur]
Behal, Helene [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Barraud-Lange, D. V. [Auteur]
Pollet-Villard, X. [Auteur]
Lengliné, E. [Auteur]
Itzykson, R. [Auteur]
Andreoli, A. [Auteur]
Ricadat, E. [Auteur]
Dhédin, N. [Auteur]
Levy, R. [Auteur]
Poirot, C. [Auteur]
Boissel, N. [Auteur]

Journal title :

Journal of Adolescent and Young Adult Oncology

Abbreviated title :

J Adolesc Young Adult Oncol

Volume number :

11

Publication date :

2022-08

ISSN :

2156-535X

English keyword(s) :

quality of life
hematological diseases
fertility preservation
sperm banking

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Purpose: Infertility in adolescents and young adult (AYA) survivors of malignant disease remains a major long-term adverse effect, but semen collection for fertility preservation in fertility centers is not always feasible ...
Show more >Purpose: Infertility in adolescents and young adult (AYA) survivors of malignant disease remains a major long-term adverse effect, but semen collection for fertility preservation in fertility centers is not always feasible and makes AYAs uncomfortable. We evaluated the feasibility of collecting sperm samples on the ward versus in fertility centers. Methods: Consecutive hospitalized AYA-aged male patients in the Hematology AYA unit (Saint-Louis Hospital, France) between August 2010 and June 2016 with hematological disease and indication of semen collection (n = 95) were included in this retrospective study. Semen quality was analyzed according to World Health Organization guidelines and was compared according to semen collection place: on the ward (n = 46) or in fertility center (n = 49). Results: The median age was median age 19.1 years (range: 13.7–33.3; interquartile range: 17.1–22.8) and 85 patients successfully collected semen. Sperm collection failure was ∼11% and was comparable between the two modalities as were main sperm quality characteristics (semen volume, sperm concentration, total sperm count, progressive motility and vitality, sperm morphology, and multiple anomalies index). Oligospermia was significantly higher in the samples obtained in fertility center (47.7%) than on the ward (26.8%), p = 0.047. Average frozen straws were comparable, 12.2 ± 6.4 on the ward versus 11.9 ± 6.3 in fertility center. Conclusion: Semen collection on the ward is feasible and would be particularly interesting for AYA male patients without altering semen quality characteristicsShow less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2023-11-15T05:35:04Z
2024-02-27T10:17:49Z