Retrograde Extraperitoneal Laparoscopic ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Retrograde Extraperitoneal Laparoscopic Prostatectomy (RELP). A Prospective Study about 1,000 Consecutive Patients, with Oncological and Functional Results
Auteur(s) :
Dubernard, P. [Auteur]
Chaffange, P. [Auteur]
Pacheco, P. [Auteur]
Pricaz, E. [Auteur]
Vaziri, N. [Auteur]
Vinet, M. [Auteur]
Chalabreysse, P. [Auteur]
Rochat, C. H. [Auteur]
Ficheur, Gregoire [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Chazard, Emmanuel [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Chaffange, P. [Auteur]
Pacheco, P. [Auteur]
Pricaz, E. [Auteur]
Vaziri, N. [Auteur]
Vinet, M. [Auteur]
Chalabreysse, P. [Auteur]
Rochat, C. H. [Auteur]
Ficheur, Gregoire [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Chazard, Emmanuel [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Titre de la revue :
Urology Journal
Nom court de la revue :
Urol J
Numéro :
18
Pagination :
p. 503-511
Date de publication :
2021-09
ISSN :
1735-546X
Mot(s)-clé(s) en anglais :
functional results
laparoscopy
oncological results
prostatectomy
prostatic neoplasms
retrograde extraperitoneal laparoscopic prostatectomy
laparoscopy
oncological results
prostatectomy
prostatic neoplasms
retrograde extraperitoneal laparoscopic prostatectomy
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Purpose: Usual laparoscopic surgery of localized prostate cancer uses antegrade dissection. We describe and evaluate the original RELP (Retrograde Extraperitoneal Laparoscopic Prostatectomy).
Materials and Methods: A ...
Lire la suite >Purpose: Usual laparoscopic surgery of localized prostate cancer uses antegrade dissection. We describe and evaluate the original RELP (Retrograde Extraperitoneal Laparoscopic Prostatectomy). Materials and Methods: A prospective cohort of 1005 patients with clinical localized cancer prostate were operated from December 1999 to September 2013, in Lyon (France), and followed up to 172 months (median: 60 months). Patients encountered a RELP procedure, a totally extra-peritoneal approach with a retrograde dissection from the apex to the bladder neck, and ascending dissection of the erectile neurovascular bundles, facilitated by the 30° optic telescope. Adjunctive treatments were: immediate radiotherapy (9.2%), salvage radiotherapy (13.4%), androgen deprivation therapy (10.8%), chemotherapy (1.4%), no treatment (75.8%). Results The mean age was 63.4, the Gleason score was 4+3 or worse in 24.9%, there were 2.3% unifocal tumors. The pathology stages were pT2A (8.71%), pT2B (2.80%), pT2C (69.0%), pT3A (13.1%), and pT3B (6.41%). There were 60.8% negative margins (R0) in total (90.1% for basal locations, and 75.8% for apical locations). The mean operating time was 115 minutes for the last 100 patients. The BPFSR (biological progression free survival rate, PSA≤0.10 ng/ml) was 71.9% at 5 years, and 61.4% at 10 years. The cancer specific survival rate was 99.4% at 5 years, and 98.3% at 10 years. After 12 months, 88.6% of patients did not require an incontinence pad, and 67.0% retained the pre-operative quality of their erection. Conclusion: RELP yields good oncologic results and quality of life, as good as robot-assisted surgery.Lire moins >
Lire la suite >Purpose: Usual laparoscopic surgery of localized prostate cancer uses antegrade dissection. We describe and evaluate the original RELP (Retrograde Extraperitoneal Laparoscopic Prostatectomy). Materials and Methods: A prospective cohort of 1005 patients with clinical localized cancer prostate were operated from December 1999 to September 2013, in Lyon (France), and followed up to 172 months (median: 60 months). Patients encountered a RELP procedure, a totally extra-peritoneal approach with a retrograde dissection from the apex to the bladder neck, and ascending dissection of the erectile neurovascular bundles, facilitated by the 30° optic telescope. Adjunctive treatments were: immediate radiotherapy (9.2%), salvage radiotherapy (13.4%), androgen deprivation therapy (10.8%), chemotherapy (1.4%), no treatment (75.8%). Results The mean age was 63.4, the Gleason score was 4+3 or worse in 24.9%, there were 2.3% unifocal tumors. The pathology stages were pT2A (8.71%), pT2B (2.80%), pT2C (69.0%), pT3A (13.1%), and pT3B (6.41%). There were 60.8% negative margins (R0) in total (90.1% for basal locations, and 75.8% for apical locations). The mean operating time was 115 minutes for the last 100 patients. The BPFSR (biological progression free survival rate, PSA≤0.10 ng/ml) was 71.9% at 5 years, and 61.4% at 10 years. The cancer specific survival rate was 99.4% at 5 years, and 98.3% at 10 years. After 12 months, 88.6% of patients did not require an incontinence pad, and 67.0% retained the pre-operative quality of their erection. Conclusion: RELP yields good oncologic results and quality of life, as good as robot-assisted surgery.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Date de dépôt :
2023-11-15T06:09:08Z
2024-04-15T11:17:10Z
2024-04-15T11:17:10Z