Association of Hypotension During Thrombectomy ...
Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
PMID :
Permalink :
Title :
Association of Hypotension During Thrombectomy and Outcomes Differs With the Posterior Communicating Artery Patency
Author(s) :
Maïer, B. [Auteur]
Robichon, E. [Auteur]
Bourcier, R. [Auteur]
ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 [ITX-lab]
Dargazanli, C. [Auteur]
Labreuche, Julien [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Thion, L. A. [Auteur]
Leguen, M. [Auteur]
Riem, R. [Auteur]
Desilles, J. P. [Auteur]
Boulouis, G. [Auteur]
Delvoye, F. [Auteur]
Hebert, S. [Auteur]
Redjem, H. [Auteur]
Smajda, S. [Auteur]
Escalard, S. [Auteur]
Blanc, R. [Auteur]
Piotin, M. [Auteur]
Lapergue, B. [Auteur]
Mazighi, M. [Auteur]
Robichon, E. [Auteur]
Bourcier, R. [Auteur]
ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 [ITX-lab]
Dargazanli, C. [Auteur]
Labreuche, Julien [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Thion, L. A. [Auteur]
Leguen, M. [Auteur]
Riem, R. [Auteur]
Desilles, J. P. [Auteur]
Boulouis, G. [Auteur]
Delvoye, F. [Auteur]
Hebert, S. [Auteur]
Redjem, H. [Auteur]
Smajda, S. [Auteur]
Escalard, S. [Auteur]
Blanc, R. [Auteur]
Piotin, M. [Auteur]
Lapergue, B. [Auteur]
Mazighi, M. [Auteur]
Journal title :
Stroke
Abbreviated title :
Stroke
Volume number :
52
Pages :
p. 2964 – 2967
Publication date :
2021-09
ISSN :
1524-4628
English keyword(s) :
blood pressure
hemodynamics
hypotension
ischemic stroke
thrombectomy
hemodynamics
hypotension
ischemic stroke
thrombectomy
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
BACKGROUND AND PURPOSE: Hypotension during endovascular therapy for acute ischemic stroke is associated with worse
functional outcomes (FO). Given its important role in intracranial hemodynamics, we investigated whether ...
Show more >BACKGROUND AND PURPOSE: Hypotension during endovascular therapy for acute ischemic stroke is associated with worse functional outcomes (FO). Given its important role in intracranial hemodynamics, we investigated whether hypotension during endovascular therapy had the same effect on FO according to the posterior communicating artery (PComA) patency. METHODS: We performed a post hoc analysis of the ASTER trial (Contact Aspiration Versus Stent Retriever for Successful Revascularization). Patients were included if they had middle cerebral artery occlusions. Primary outcome was favorable FO, defined by a modified Rankin Scale scores between 0 and 2 at 3 months. RESULTS: One hundred forty-eight patients with middle cerebral artery occlusion were included. In patients with no PComA, an increase in minimum mean arterial pressure was positively associated with favorable FO (odds ratio per 10 mm Hg increase, 1.59 [95%CI, 1.11–2.25]; P=0.010), whereas no association was found in patients with a PComA (odds ratio, 0.77 [95% CI, 0.54–1.08]; P=0.12). Patients with no PComA and longer cumulative time with mean arterial pressure <90 mm Hg or systolic blood pressure <140 mm Hg had significantly lower rates of favorable FO, with an odds ratio per 10-minute increase of 0.75 (95% CI, 0.59–0.94; P=0.010) and 0.74 (95% CI, 0.60–0.91; P=0.003), but not in patients with a PComA. CONCLUSIONS: Hypotension during endovascular therapy for middle cerebral artery occlusion is consistently associated with worse FO in patients with no PComA but not in those with a PComA.Show less >
Show more >BACKGROUND AND PURPOSE: Hypotension during endovascular therapy for acute ischemic stroke is associated with worse functional outcomes (FO). Given its important role in intracranial hemodynamics, we investigated whether hypotension during endovascular therapy had the same effect on FO according to the posterior communicating artery (PComA) patency. METHODS: We performed a post hoc analysis of the ASTER trial (Contact Aspiration Versus Stent Retriever for Successful Revascularization). Patients were included if they had middle cerebral artery occlusions. Primary outcome was favorable FO, defined by a modified Rankin Scale scores between 0 and 2 at 3 months. RESULTS: One hundred forty-eight patients with middle cerebral artery occlusion were included. In patients with no PComA, an increase in minimum mean arterial pressure was positively associated with favorable FO (odds ratio per 10 mm Hg increase, 1.59 [95%CI, 1.11–2.25]; P=0.010), whereas no association was found in patients with a PComA (odds ratio, 0.77 [95% CI, 0.54–1.08]; P=0.12). Patients with no PComA and longer cumulative time with mean arterial pressure <90 mm Hg or systolic blood pressure <140 mm Hg had significantly lower rates of favorable FO, with an odds ratio per 10-minute increase of 0.75 (95% CI, 0.59–0.94; P=0.010) and 0.74 (95% CI, 0.60–0.91; P=0.003), but not in patients with a PComA. CONCLUSIONS: Hypotension during endovascular therapy for middle cerebral artery occlusion is consistently associated with worse FO in patients with no PComA but not in those with a PComA.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Submission date :
2023-11-15T06:22:32Z
2024-02-14T10:19:17Z
2024-02-14T10:19:17Z