REview of potentially inappropriate ...
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Article dans une revue scientifique: Article original
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Title :
REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors (REMEDI[e]S): French implicit and explicit criteria
Author(s) :
Roux, B. [Auteur]
Berthou-Contreras, J. [Auteur]
Beuscart, Jean-Baptiste [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Charenton-Blavignac, M. [Auteur]
Doucet, J. [Auteur]
Fournier, J. P. [Auteur]
De La Gastine, B. [Auteur]
Gautier, Sophie [Auteur]
Gonthier, R. [Auteur]
Gras, V. [Auteur]
Grau, M. [Auteur]
Noize, P. [Auteur]
Polard, E. [Auteur]
Rudelle, K. [Auteur]
Valnet-Rabier, M. B. [Auteur]
Tannou, T. [Auteur]
Laroche, M. L. [Auteur]
Berthou-Contreras, J. [Auteur]
Beuscart, Jean-Baptiste [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Charenton-Blavignac, M. [Auteur]
Doucet, J. [Auteur]
Fournier, J. P. [Auteur]
De La Gastine, B. [Auteur]
Gautier, Sophie [Auteur]
Gonthier, R. [Auteur]
Gras, V. [Auteur]
Grau, M. [Auteur]
Noize, P. [Auteur]
Polard, E. [Auteur]
Rudelle, K. [Auteur]
Valnet-Rabier, M. B. [Auteur]
Tannou, T. [Auteur]
Laroche, M. L. [Auteur]
Journal title :
European Journal of Clinical Pharmacology
Abbreviated title :
Eur J Clin Pharmacol
Volume number :
77
Pages :
p. 1713–1724
Publication date :
2021
ISSN :
1432-1041
English keyword(s) :
Older adults
Inappropriate prescribing
Implicit criteria
Explicit criteria
Delphi method
France
Inappropriate prescribing
Implicit criteria
Explicit criteria
Delphi method
France
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Purpose
To establish a consensus on both explicit and implicit criteria in order to identify potentially inappropriate prescribing (PIP) in French older people aged 75 years and over or 65 years and over with ...
Show more >Purpose To establish a consensus on both explicit and implicit criteria in order to identify potentially inappropriate prescribing (PIP) in French older people aged 75 years and over or 65 years and over with multimorbidity. Methods Fifteen experts in geriatrics, general practice, pharmacy, and clinical pharmacology were involved in a two-round Delphi survey to assess preliminary explicit and implicit criteria based on an extensive literature review and up-to-date evidence data. Experts were asked to rate their level of agreement using a 5-level Likert scale for inclusion of criteria and also for rationale and therapeutic alternatives. A consensus was considered as reached if at least 75% of the experts rated criteria as “strongly agreed” or “agreed.” Results The new tool included a seven-step algorithm (implicit criteria) encompassing the three main domains that define PIP (i.e. overprescribing, underprescribing, and misprescribing) and 104 explicit criteria. Explicit criteria were divided into 6 tables related to inappropriate drug duplications (n = 7 criteria), omissions of medications and/or medication associations (n = 16), medications with an unfavourable benefit/risk ratio and/or a questionable efficacy (n = 39), medications with an unsuitable dose (n = 4) or duration (n = 6), drug-disease (n = 13), and drug-drug interactions (n = 19). Conclusion The REMEDI[e]S tool (REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors) is an original mixed tool, adapted to French medical practices, aimed at preventing PIP both at the individual level in clinical practice and the population level in large-scale studies. Therefore, its use could contribute to an improvement in healthcare professionals’ prescribing practices and safer care in older adults.Show less >
Show more >Purpose To establish a consensus on both explicit and implicit criteria in order to identify potentially inappropriate prescribing (PIP) in French older people aged 75 years and over or 65 years and over with multimorbidity. Methods Fifteen experts in geriatrics, general practice, pharmacy, and clinical pharmacology were involved in a two-round Delphi survey to assess preliminary explicit and implicit criteria based on an extensive literature review and up-to-date evidence data. Experts were asked to rate their level of agreement using a 5-level Likert scale for inclusion of criteria and also for rationale and therapeutic alternatives. A consensus was considered as reached if at least 75% of the experts rated criteria as “strongly agreed” or “agreed.” Results The new tool included a seven-step algorithm (implicit criteria) encompassing the three main domains that define PIP (i.e. overprescribing, underprescribing, and misprescribing) and 104 explicit criteria. Explicit criteria were divided into 6 tables related to inappropriate drug duplications (n = 7 criteria), omissions of medications and/or medication associations (n = 16), medications with an unfavourable benefit/risk ratio and/or a questionable efficacy (n = 39), medications with an unsuitable dose (n = 4) or duration (n = 6), drug-disease (n = 13), and drug-drug interactions (n = 19). Conclusion The REMEDI[e]S tool (REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors) is an original mixed tool, adapted to French medical practices, aimed at preventing PIP both at the individual level in clinical practice and the population level in large-scale studies. Therefore, its use could contribute to an improvement in healthcare professionals’ prescribing practices and safer care in older adults.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Submission date :
2023-11-15T06:24:12Z
2024-03-13T10:03:10Z
2024-03-13T10:03:10Z