Predictive value of 4th post-operative-day ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Predictive value of 4th post-operative-day CRP in the early detection of complications after laparoscopic bowel resection for endometriosis
Auteur(s) :
Pécheux, O. [Auteur]
Dilé, P. [Auteur]
Kerbage, Yohan [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Piessen, Guillaume [Auteur]
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Deken, Valerie [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Collinet, Pierre [Auteur]
Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Rubod Dit Guillet, Chrystele [Auteur]
Laboratoire de Mécanique, Multi-physique, Multi-échelle (LaMcube) - UMR 9013
Dilé, P. [Auteur]
Kerbage, Yohan [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Piessen, Guillaume [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Deken, Valerie [Auteur]
![refId](/themes/Mirage2//images/idref.png)
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Collinet, Pierre [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Rubod Dit Guillet, Chrystele [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Laboratoire de Mécanique, Multi-physique, Multi-échelle (LaMcube) - UMR 9013
Titre de la revue :
Journal of Gynecology Obstetrics and Human Reproduction
Nom court de la revue :
J Gynecol Obstet Hum Reprod
Numéro :
50
Pagination :
102148
Date de publication :
2021-11
ISSN :
2468-7847
Mot(s)-clé(s) en anglais :
Endometriosis
CRP
Bowel resection
Anastomotic leak
Post-operative complication
CRP
Bowel resection
Anastomotic leak
Post-operative complication
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Objective
Post-operative CRP on postoperative day 4 (POD) is used for the early detection of complications after colorectal surgery for cancer, but there is no evidence yet that justifies the use of this marker for bowel ...
Lire la suite >Objective Post-operative CRP on postoperative day 4 (POD) is used for the early detection of complications after colorectal surgery for cancer, but there is no evidence yet that justifies the use of this marker for bowel resection in case of endometriosis. Study design We retrospectively included 66 consecutive patients who underwent bowel resection for endometriosis (stage 4) in Lille university hospital, France, from August 1, 2015 until January 31, 2017. The composite endpoint of our study included anastomotic leakages, infectious or thrombo-embolic complications, hematomas, bowel stenosis, rectorrhagia, voiding dysfunction, and rehospitalization for related symptoms. Results CRP on POD 4 presents a satisfying area under the curve of 0.85, for the composite endpoint. A CRP cut off value of 56 mg/L yielded a sensitivity of 0.61 (IC95%: 0.36 to 0.83) and a specificity of 0.98 (IC95%: 0.89 to 1). The negative and positive predictive values were 0.87 and 0.92. Conclusion The negative predictive value of the CRP on POD 4 after bowel resection for endometriosis is a useful early indicator for detecting a complication. Therefore, this biomarker might be safely used as an additional criterion for a safe discharge from hospital after colorectal resection in endometriosis.Lire moins >
Lire la suite >Objective Post-operative CRP on postoperative day 4 (POD) is used for the early detection of complications after colorectal surgery for cancer, but there is no evidence yet that justifies the use of this marker for bowel resection in case of endometriosis. Study design We retrospectively included 66 consecutive patients who underwent bowel resection for endometriosis (stage 4) in Lille university hospital, France, from August 1, 2015 until January 31, 2017. The composite endpoint of our study included anastomotic leakages, infectious or thrombo-embolic complications, hematomas, bowel stenosis, rectorrhagia, voiding dysfunction, and rehospitalization for related symptoms. Results CRP on POD 4 presents a satisfying area under the curve of 0.85, for the composite endpoint. A CRP cut off value of 56 mg/L yielded a sensitivity of 0.61 (IC95%: 0.36 to 0.83) and a specificity of 0.98 (IC95%: 0.89 to 1). The negative and positive predictive values were 0.87 and 0.92. Conclusion The negative predictive value of the CRP on POD 4 after bowel resection for endometriosis is a useful early indicator for detecting a complication. Therefore, this biomarker might be safely used as an additional criterion for a safe discharge from hospital after colorectal resection in endometriosis.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
- Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
- Laboratoire de Mécanique, Multi-physique, Multi-échelle (LaMcube) - UMR 9013
- METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
- Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Date de dépôt :
2023-11-15T06:51:32Z
2024-03-13T10:13:27Z
2024-03-13T10:13:27Z