National early warning score to predict ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
National early warning score to predict intensive care unit transfer and mortality in COVID-19 in a French cohort
Auteur(s) :
Pokeerbux, M. R. [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Yelnik, C. M. [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Faure, Emmanuel [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Drumez, Elodie [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Bruandet, Amelie [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Labreuche, Julien [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Assaf, A. [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Goffard, Anne [Auteur]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
Garabedian, Charles [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Poissy, Julien [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle (UGSF) - UMR 8576
Desbordes, J. [Auteur]
Garrigue, D. [Auteur]
Scherpereel, A. [Auteur]
Faure, Karine [Auteur]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
Lambert, Marc [Auteur]
Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167
Covid-Team, L. [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Yelnik, C. M. [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Faure, Emmanuel [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Drumez, Elodie [Auteur]

METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Bruandet, Amelie [Auteur]

METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Labreuche, Julien [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Assaf, A. [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Goffard, Anne [Auteur]

Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
Garabedian, Charles [Auteur]

METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Poissy, Julien [Auteur]

Unité de Glycobiologie Structurale et Fonctionnelle (UGSF) - UMR 8576
Desbordes, J. [Auteur]
Garrigue, D. [Auteur]
Scherpereel, A. [Auteur]
Faure, Karine [Auteur]

Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
Lambert, Marc [Auteur]

Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167
Covid-Team, L. [Auteur]
Titre de la revue :
The International journal of clinical practice
Nom court de la revue :
Int J Clin Pract
Numéro :
75
Pagination :
e14121
Date de publication :
2021-06
ISSN :
1742-1241
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Background
No risk stratification tool has been validated in hospitalised patients with coronavirus disease 2019 (COVID-19), despite a high rate of intensive care requirement and in-hospital mortality. We aimed to ...
Lire la suite >Background No risk stratification tool has been validated in hospitalised patients with coronavirus disease 2019 (COVID-19), despite a high rate of intensive care requirement and in-hospital mortality. We aimed to determine whether the National Early Warning Score (NEWS) at admission can accurately predict in-hospital mortality and ICU transfer. Methods This was a retrospective cohort study from January 24 to April 16, 2020, at Lille University Hospital. All consecutive adult patients with laboratory-confirmed COVID-19 who were initially admitted to non-ICU wards were included. The primary outcome was a composite criterion consisting of ICU transfer or in-hospital mortality. We evaluated the prognostic performance of NEWS by calculating the area under (AUC) the receiver operating characteristic curve, the optimal threshold value of NEWS, and its association with the primary outcome. Results Of the 202 COVID-19 patients, the median age was 65 (interquartile range 52-78), 38.6% were women and 136 had at least one comorbidity. The median NEWS was 4 (2-6). A total of 65 patients were transferred to the ICU or died in the hospital. Compared with patients with favourable outcome, these patients were significantly older, had more comorbidities and higher NEWS. The AUC for NEWS was 0.68 (0.60-0.77) and the best cutoff value was 6. Adjusted odds ratio for NEWS ≥ 6 as an independent predictor was 3.78 (1.94-7.09). Conclusions In hospitalised COVID-19 patients, NEWS was an independent predictor of ICU transfer and in-hospital death. In daily practice, NEWS ≥ 6 at admission may help to identify patients who are at risk to deteriorate.Lire moins >
Lire la suite >Background No risk stratification tool has been validated in hospitalised patients with coronavirus disease 2019 (COVID-19), despite a high rate of intensive care requirement and in-hospital mortality. We aimed to determine whether the National Early Warning Score (NEWS) at admission can accurately predict in-hospital mortality and ICU transfer. Methods This was a retrospective cohort study from January 24 to April 16, 2020, at Lille University Hospital. All consecutive adult patients with laboratory-confirmed COVID-19 who were initially admitted to non-ICU wards were included. The primary outcome was a composite criterion consisting of ICU transfer or in-hospital mortality. We evaluated the prognostic performance of NEWS by calculating the area under (AUC) the receiver operating characteristic curve, the optimal threshold value of NEWS, and its association with the primary outcome. Results Of the 202 COVID-19 patients, the median age was 65 (interquartile range 52-78), 38.6% were women and 136 had at least one comorbidity. The median NEWS was 4 (2-6). A total of 65 patients were transferred to the ICU or died in the hospital. Compared with patients with favourable outcome, these patients were significantly older, had more comorbidities and higher NEWS. The AUC for NEWS was 0.68 (0.60-0.77) and the best cutoff value was 6. Adjusted odds ratio for NEWS ≥ 6 as an independent predictor was 3.78 (1.94-7.09). Conclusions In hospitalised COVID-19 patients, NEWS was an independent predictor of ICU transfer and in-hospital death. In daily practice, NEWS ≥ 6 at admission may help to identify patients who are at risk to deteriorate.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
- Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
- Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167
- METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
- Unité de Glycobiologie Structurale et Fonctionnelle (UGSF) - UMR 8576
Date de dépôt :
2023-11-15T07:09:49Z
2023-12-04T10:45:35Z
2024-02-27T14:17:49Z
2024-03-27T07:51:03Z
2023-12-04T10:45:35Z
2024-02-27T14:17:49Z
2024-03-27T07:51:03Z
Fichiers
- P21.76 Poissy J 2021 Int J Clin Pract. 2021;75(6) e14121 (1).pdf
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