Trends in Antibiotic Consumption and ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Trends in Antibiotic Consumption and Resistance in France Over 20 Years: Large and Continuous Efforts but Contrasting Results.
Auteur(s) :
Carlet, Jean [Auteur]
Haute Autorité de Santé [Saint-Denis La Plaine] [HAS]
Jarlier, Vincent [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Acar, Jacques [Auteur]
Université Pierre et Marie Curie - Paris 6 [UPMC]
Debaere, Olivier [Auteur]
Ministère de l'Alimentation, de l'Agriculture et de la Pêche [Paris, France]
Dehaumont, Patrick [Auteur]
Ministère de l'Alimentation, de l'Agriculture et de la Pêche [Paris, France]
Grandbastien, Bruno [Auteur]
Le Coz, Pierre [Auteur]
Lina, Gérard [Auteur]
Institut des Agents Infectieux [Lyon] [IAI]
Pean, Yves [Auteur]
Rambaud, Claude [Auteur]
Salomon, Jerôme [Auteur]
Ministère des Solidarités et de la Santé [Paris, France]
Schlemmer, Benoit [Auteur]
Université Paris Diderot - Paris 7 [UPD7]
Tattevin, Pierre [Auteur]
Service des maladies infectieuses et réanimation médicale [Rennes] = Infectious Disease and Intensive Care [Rennes]
VALLET, BENOIT [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Haute Autorité de Santé [Saint-Denis La Plaine] [HAS]
Jarlier, Vincent [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Acar, Jacques [Auteur]
Université Pierre et Marie Curie - Paris 6 [UPMC]
Debaere, Olivier [Auteur]
Ministère de l'Alimentation, de l'Agriculture et de la Pêche [Paris, France]
Dehaumont, Patrick [Auteur]
Ministère de l'Alimentation, de l'Agriculture et de la Pêche [Paris, France]
Grandbastien, Bruno [Auteur]
Le Coz, Pierre [Auteur]
Lina, Gérard [Auteur]
Institut des Agents Infectieux [Lyon] [IAI]
Pean, Yves [Auteur]
Rambaud, Claude [Auteur]
Salomon, Jerôme [Auteur]
Ministère des Solidarités et de la Santé [Paris, France]
Schlemmer, Benoit [Auteur]
Université Paris Diderot - Paris 7 [UPD7]
Tattevin, Pierre [Auteur]
Service des maladies infectieuses et réanimation médicale [Rennes] = Infectious Disease and Intensive Care [Rennes]
VALLET, BENOIT [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Titre de la revue :
Open Forum Infectious Diseases
Nom court de la revue :
Open Forum Infect Dis
Numéro :
7
Pagination :
ofaa452
Date de publication :
2020-11-20
ISSN :
2328-8957
Mot(s)-clé(s) en anglais :
antibiotics
antibiotic consumption
antibiotic resistance
bacterial transmission
gram-negative bacilli
gram-positive cocci
antibiotic consumption
antibiotic resistance
bacterial transmission
gram-negative bacilli
gram-positive cocci
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Background
Antimicrobial resistance (AMR) is a serious threat to humanity. This paper describes the French efforts made since 2001 and presents data on antimicrobial consumption (AC) and AMR.
Methods
We gathered all ...
Lire la suite >Background Antimicrobial resistance (AMR) is a serious threat to humanity. This paper describes the French efforts made since 2001 and presents data on antimicrobial consumption (AC) and AMR. Methods We gathered all data on AC and AMR recorded since 2001 from different national agencies, transferred on a regular basis to standardized European data on AC and resistance in both humans and animals. Results After a large information campaign implemented in France from 2001 to 2005 in humans, AC in the community decreased significantly (18% to 34% according to the calculation method used). It remained at the same level from 2005 to 2010 and increased again from 2010 to 2018 (8%). Contrasting results were observed for AMR. The resistance of Staphylococcus aureus decreased significantly. For gram-negative bacilli, the results were variable according to the microorganism. The resistance of Enterobacteriaceae to third-generation cephalosporins increased, remaining moderate for Escherichia coli (12% in 2017) but reaching 35% in the same year for Klebsiella pneumoniae. Resistance to carbapenems in those 2 microorganisms remained below 1%. Both global AC and resistance to most antibiotics decreased significantly in animals. Conclusions Antibiotic consumption decreased significantly in France after a large public campaign from 2001 to 2005, but this positive effect was temporary. The effect on AMR varied according to the specific microorganism: The effect was very impressive for gram-positive cocci, variable for gram-negative bacilli, and moderate for E. coli, but that for K. pneumoniae was of concern. The consumption of and resistance to antibiotics decreased significantly in animals.Lire moins >
Lire la suite >Background Antimicrobial resistance (AMR) is a serious threat to humanity. This paper describes the French efforts made since 2001 and presents data on antimicrobial consumption (AC) and AMR. Methods We gathered all data on AC and AMR recorded since 2001 from different national agencies, transferred on a regular basis to standardized European data on AC and resistance in both humans and animals. Results After a large information campaign implemented in France from 2001 to 2005 in humans, AC in the community decreased significantly (18% to 34% according to the calculation method used). It remained at the same level from 2005 to 2010 and increased again from 2010 to 2018 (8%). Contrasting results were observed for AMR. The resistance of Staphylococcus aureus decreased significantly. For gram-negative bacilli, the results were variable according to the microorganism. The resistance of Enterobacteriaceae to third-generation cephalosporins increased, remaining moderate for Escherichia coli (12% in 2017) but reaching 35% in the same year for Klebsiella pneumoniae. Resistance to carbapenems in those 2 microorganisms remained below 1%. Both global AC and resistance to most antibiotics decreased significantly in animals. Conclusions Antibiotic consumption decreased significantly in France after a large public campaign from 2001 to 2005, but this positive effect was temporary. The effect on AMR varied according to the specific microorganism: The effect was very impressive for gram-positive cocci, variable for gram-negative bacilli, and moderate for E. coli, but that for K. pneumoniae was of concern. The consumption of and resistance to antibiotics decreased significantly in animals.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Date de dépôt :
2023-11-15T07:46:35Z
2023-12-18T15:16:57Z
2023-12-18T15:16:57Z
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