Title :

How to handle concomitant asymptomatic prosthetic joints during an episode of hematogenous PJI, a multicentre analysis.

Author(s) :

Wouthuyzen-Bakker, Marjan [Auteur]
University of Groningen [Groningen]
Sebillotte, Marine [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Arvieux, Cédric [Auteur]
Service des maladies infectieuses et réanimation médicale [Rennes] = Infectious Disease and Intensive Care [Rennes]
Fernandez-Sampedro, Marta [Auteur]
Hospital Universitario Marqués de Valdecilla [Santander]
Senneville, Eric [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Barbero, José Maria [Auteur]
Lora-Tamayo, Jaime [Auteur]
Hospital Universitario Doce de Octubre
Aboltins, Craig [Auteur]
University of Melbourne
Trebse, Rihard [Auteur]
University Medical Centre Ljubljana [Ljubljana, Slovenia] [UMCL]
Salles, Mauro José [Auteur]
Federal University of Sao Paulo [Unifesp]
Kramer, Tobias Siegfried [Auteur]
Charité - UniversitätsMedizin = Berlin University Medicine
Ferrari, Matteo [Auteur]
Humanitas University [Milan] [Hunimed]
Garcia-Cañete, Joaquín [Auteur]
Universidad Autónoma de Madrid [UAM]
Benito, Natividad [Auteur]
Universitat Autònoma de Barcelona = Autonomous University of Barcelona = Universidad Autónoma de Barcelona [UAB]
Diaz-Brito, Vicens [Auteur]
Parc Sanitari Sant Joan de Déu [Espagne]
Del Toro, Maria Dolores [Auteur]
Hospital Universitario Virgen Macarena [Séville]
Scarborough, Matthew [Auteur]
University of Oxford
Soriano, Alex [Auteur]

Journal title :

Clinical Infectious Diseases

Abbreviated title :

Clin. Infect. Dis.

Volume number :

73

Pages :

e3820–e3824

Publication date :

2020-08-22

ISSN :

1537-6591

English keyword(s) :

periprosthetic joint infection
late acute
hematogenous
asymptomatic
bacteremia

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background Prosthetic joints are at risk of becoming infected during an episode of bacteremia, especially during Staphylocococcus aureus bacteremia. However, it is unclear how often asymptomatic periprosthetic joint ...
Show more >Background Prosthetic joints are at risk of becoming infected during an episode of bacteremia, especially during Staphylocococcus aureus bacteremia. However, it is unclear how often asymptomatic periprosthetic joint infection (PJI) occurs, and whether additional diagnostics should be considered. Methods In this multicenter study, we retrospectively analyzed a cohort of patients with a late acute (hematogenous) PJI between 2005–2015 who had concomitant prosthetic joints in situ. Patients without at least 1 year of follow-up were excluded. Results We included 91 patients with a hematogenous PJI and 108 concomitant prosthetic joints. The incident PJI was most frequently caused by Staphylococcus aureus (43%), followed by streptococci (26%) and Gram-negative rods (18%). Of 108 concomitant prosthetic joints, 13 were symptomatic, of which 10 were subsequently diagnosed as a second PJI. Of the 95 asymptomatic prosthetic joints, 1 PJI developed during the follow-up period and was classified as a “missed” PJI at the time of bacteremia with S. aureus (1.1%). Infected prosthetic joints were younger than the noninfected ones in 67% of cases, and prosthetic knees were affected more often than prosthetic hips (78%). Conclusions During an episode of hematogenous PJI, concomitant asymptomatic prosthetic joints have a very low risk of being infected, and additional diagnostic work-up for these joints is not necessary.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2023-11-15T08:18:10Z
2023-12-18T14:06:15Z