Titre :

A snapshot of the Covid-19 pandemic among pregnant women in France.

Auteur(s) :

Kayem, Gilles [Auteur]
CHU Trousseau [APHP]
Lecarpentier, Edouard [Auteur]
Centre Hospitalier Intercommunal de Créteil [CHIC]
Deruelle, Philippe [Auteur]

Bretelle, Florence [Auteur]
Microbes évolution phylogénie et infections [MEPHI]
Azria, Elie [Auteur]
Groupe Hospitalier Paris Saint-Joseph [hpsj]
Blanc, Julie [Auteur]
Hôpital Nord [CHU - APHM]
Bohec, Caroline [Auteur]
Centre hospitalier de Pau
Bornes, Marie [Auteur]
CHU Tenon [AP-HP]
Ceccaldi, Pierre-François [Auteur]
Université Paris Diderot - Paris 7 [UPD7]
Chalet, Yasmine [Auteur]
INSERM UMR-S 606, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, PRES Sorbonne Paris-Cité, and Université Paris Denis Diderot,
Chauleur, Céline [Auteur]
Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] [CHU ST-E]
Cordier, Anne-Gael [Auteur]
Université Paris-Sud - Paris 11 [UP11]
Desbrière, Raoul [Auteur]
Hôpital Saint-Joseph [Marseille]
Doret, Muriel [Auteur]
Dreyfus, Michel [Auteur]
CHU Caen
Driessen, Marine [Auteur]
Recherche Epidémiologique en Santé Périnatale et Santé des Femmes et des Enfants [UMR_S 953]
Fermaut, Marion [Auteur]
Université Paris 13 [UP13]
Gallot, Denis [Auteur]
CHU Estaing [Clermont-Ferrand]
Garabedian, Charles [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Huissoud, Cyril [Auteur]
Hôpital de la Croix-Rousse [CHU - HCL]
Luton, Dominique [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Morel, Olivier [Auteur]
Maternité Régionale Adolphe Pinard [Nancy]
Perrotin, Franck [Auteur]
CHU Trousseau [Tours]
Picone, Olivier [Auteur]
Hôpital Louis Mourier - AP-HP [Colombes]
Rozenberg, Patrick [Auteur]
CHI Poissy-Saint-Germain
Sentilhes, Loïc [Auteur]

Sroussi, Jeremy [Auteur]
INSERM UMR-S 606, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, PRES Sorbonne Paris-Cité, and Université Paris Denis Diderot,
Vayssière, Christophe [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Verspyck, Eric [Auteur]
CHU Rouen
Vivanti, Alexandre J. [Auteur]
AP-HP. Université Paris Saclay
Winer, Norbert [Auteur]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Alessandrini, Vivien [Auteur]
Hôpital Cochin [AP-HP]
Schmitz, Thomas [Auteur]
AP-HP Hôpital universitaire Robert-Debré [Paris]

Titre de la revue :

Journal of Gynecology Obstetrics and Human Reproduction

Nom court de la revue :

J Gynecol Obstet Hum Reprod

Numéro :

49

Pagination :

101826

Date de publication :

2020-06-13

ISSN :

2468-7847

Mot(s)-clé(s) en anglais :

COVID 19
Respiratory complications
Risk factors
Lockdown

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Objective To describe the course over time of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in French women from the beginning of the pandemic until mid-April, the risk profile of women with ...
Lire la suite >Objective To describe the course over time of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in French women from the beginning of the pandemic until mid-April, the risk profile of women with respiratory complications, and short-term pregnancy outcomes. Methods We collected a case series of pregnant women with COVID-19 in a research network of 33 French maternity units between March 1 and April 14, 2020. All cases of SARS-CoV-2 infection confirmed by a positive result on real-time reverse transcriptase polymerase chain reaction tests of a nasal sample and/or diagnosed by a computed tomography chest scan were included and analyzed. The primary outcome measures were COVID-19 requiring oxygen (oxygen therapy or noninvasive ventilation) and critical COVID-19 (requiring invasive mechanical ventilation or extracorporeal membrane oxygenation, ECMO). Demographic data, baseline comorbidities, and pregnancy outcomes were also collected. Results Active cases of COVID-19 increased exponentially during March 1–31, 2020; the numbers fell during April 1–14, after lockdown was imposed on March 17. The shape of the curve of active critical COVID-19 mirrored that of all active cases. By April 14, among the 617 pregnant women with COVID-19, 93 women (15.1 %; 95 %CI 12.3–18.1) had required oxygen therapy and 35 others (5.7 %; 95 %CI 4.0–7.8) had had a critical form of COVID-19. The severity of the disease was associated with age older than 35 years and obesity, as well as preexisting diabetes, previous preeclampsia, and gestational hypertension or preeclampsia. One woman with critical COVID-19 died (0.2 %; 95 %CI 0−0.9). Among the women who gave birth, rates of preterm birth in women with non-severe, oxygen-requiring, and critical COVID-19 were 13/123 (10.6 %), 14/29 (48.3 %), and 23/29 (79.3 %) before 37 weeks and 3/123 (2.4 %), 4/29 (13.8 %), and 14/29 (48.3 %) before 32 weeks, respectively. One neonate (0.5 %; 95 %CI 0.01–2.9) in the critical group died from prematurity. Conclusion COVID-19 can be responsible for significant rates of severe acute, potentially deadly, respiratory distress syndromes. The most vulnerable pregnant women, those with comorbidities, may benefit particularly from prevention measures such as a lockdown.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2023-11-15T08:45:26Z
2023-12-18T10:15:48Z