Cholesterol and Egg Intakes, and Risk of ...
Document type :
Article dans une revue scientifique: Article original
DOI :
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Title :
Cholesterol and Egg Intakes, and Risk of Hypertension in a Large Prospective Cohort of French Women.
Author(s) :
Macdonald, Conor-James [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Madika, Anne-Laure [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Bonnet, Fabrice [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Centre Hospitalier Universitaire [Rennes]
Fagherazzi, Guy [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Lajous, Martin [Auteur]
National Institute of Public Health = Instituto Nacional de Salud Pública [Cuernavaca, Mexique] [INSP]
Boutron-Ruault, Marie-Christine [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Centre de recherche en épidémiologie et santé des populations [CESP]
Madika, Anne-Laure [Auteur]

METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Bonnet, Fabrice [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Centre Hospitalier Universitaire [Rennes]
Fagherazzi, Guy [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Lajous, Martin [Auteur]
National Institute of Public Health = Instituto Nacional de Salud Pública [Cuernavaca, Mexique] [INSP]
Boutron-Ruault, Marie-Christine [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Journal title :
Nutrients
Abbreviated title :
Nutrients
Volume number :
12
Pages :
1350
Publication date :
2020-05-16
ISSN :
2072-6643
English keyword(s) :
eggs
hypertension
cholesterol
epidemiology
prospective studies
hypertension
cholesterol
epidemiology
prospective studies
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Purpose: The relationship between egg and cholesterol intakes, and cardiovascular disease is controversial. Meta-analyses indicate that egg consumption is associated with increased cardiovascular disease and mortality, but ...
Show more >Purpose: The relationship between egg and cholesterol intakes, and cardiovascular disease is controversial. Meta-analyses indicate that egg consumption is associated with increased cardiovascular disease and mortality, but reduced incidence of hypertension, a major risk factor for cardiovascular disease. This study aims to investigate the associations between consumption of egg and cholesterol, and hypertension risk in a cohort of French women. Methods: We used data from the E3N cohort study, a French prospective population-based study initiated in 1990. From the women in the study, we included those who completed a detailed diet history questionnaire, and who did not have prevalent hypertension or cardiovascular disease at baseline, resulting in 46,424 women. Hypertension cases were self-reported. Egg and cholesterol intake was estimated from dietary history questionnaires. Cox proportional hazard models with time-updated exposures were used to calculate hazard ratios. Spline regression was used to determine any dose–respondent relationship. Results: During 885,321 person years, 13,161 cases of incident hypertension were identified. Higher cholesterol consumption was associated with an increased risk of hypertension: HRQ1–Q5 = 1.22 [1.14:1.30], with associations similar regarding egg consumption up to seven eggs per week: HR4–7 eggs = 1.14 [1.06:1.18]. Evidence for a non-linear relationship between hypertension and cholesterol intake was observed. Conclusions: Egg and cholesterol intakes were associated with a higher risk of hypertension in French women. These results merit further investigation in other populations.Show less >
Show more >Purpose: The relationship between egg and cholesterol intakes, and cardiovascular disease is controversial. Meta-analyses indicate that egg consumption is associated with increased cardiovascular disease and mortality, but reduced incidence of hypertension, a major risk factor for cardiovascular disease. This study aims to investigate the associations between consumption of egg and cholesterol, and hypertension risk in a cohort of French women. Methods: We used data from the E3N cohort study, a French prospective population-based study initiated in 1990. From the women in the study, we included those who completed a detailed diet history questionnaire, and who did not have prevalent hypertension or cardiovascular disease at baseline, resulting in 46,424 women. Hypertension cases were self-reported. Egg and cholesterol intake was estimated from dietary history questionnaires. Cox proportional hazard models with time-updated exposures were used to calculate hazard ratios. Spline regression was used to determine any dose–respondent relationship. Results: During 885,321 person years, 13,161 cases of incident hypertension were identified. Higher cholesterol consumption was associated with an increased risk of hypertension: HRQ1–Q5 = 1.22 [1.14:1.30], with associations similar regarding egg consumption up to seven eggs per week: HR4–7 eggs = 1.14 [1.06:1.18]. Evidence for a non-linear relationship between hypertension and cholesterol intake was observed. Conclusions: Egg and cholesterol intakes were associated with a higher risk of hypertension in French women. These results merit further investigation in other populations.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Submission date :
2023-11-15T08:54:03Z
2023-12-19T13:44:13Z
2023-12-19T13:44:13Z
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