Titre :

Modelling and optimisation of gas-liquid mass transfer in a microporous hollow fiber membrane aerated bioreactor used to produce surfactin

Auteur(s) :

BERTH, Alexandre [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Institut Charles Viollette (ICV) - ULR 7394
Lecouturier, Didier [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Institut Charles Viollette (ICV) - ULR 7394
Loubiere, Karine [Auteur]
Dhulster, Pascal [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Institut Charles Viollette (ICV) - ULR 7394
Delaplace, Guillaume [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Unité Matériaux et Transformations (UMET) - UMR 8207

Titre de la revue :

Biochemical Engineering Journal

Numéro :

145

Pagination :

109-119

Éditeur :

elsevier

Date de publication :

2019-05-15

Mot(s)-clé(s) en anglais :

Membrane aerated bioreactor
Surfactin production
Aeration
Dimensional analysis
Experimental design
Process relationship

Discipline(s) HAL :

Sciences du Vivant [q-bio]/Ingénierie des aliments
Physique [physics]/Matière Condensée [cond-mat]/Science des matériaux [cond-mat.mtrl-sci]
Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire
Physique [physics]/Matière Condensée [cond-mat]/Matière Molle [cond-mat.soft]
Sciences de l'ingénieur [physics]/Génie des procédés

Résumé en anglais : [en]

Aeration by a membrane contactor is a convenient method to produce surfactin, a bacterial surfactant compound, while avoiding foam to overflow as it is the case with most of aerated bioreactors equipped with gas sparger. ...
Lire la suite >Aeration by a membrane contactor is a convenient method to produce surfactin, a bacterial surfactant compound, while avoiding foam to overflow as it is the case with most of aerated bioreactors equipped with gas sparger. This work helps improving knowledge on oxygen transfer in membrane-aerated bioreactors and optimizing the adjustment of culture aeration performances. In this work, oxygenation of a surfactin solution was studied in a bioreactor aerated by a microporous hollow fiber membrane contactor. First, a dimensional analysis was coupled in an innovative way with a fractional design of experiments, thus reducing greatly the number of experiments. Then, the analysis of the model helped to understand thoroughly the influence of the four main parameters, namely the liquid flow rate inside the fibers, the gas pressure outside the fibers, the liquid volume in the tank and the amount of surfactant in the bulk. Empirical process relationships were proposed to predict either the volumetric oxygen transfer coefficient (kLa) or the liquid-side oxygen transfer coefficient (kL) (with an average standard deviation < 11%). The liquid flow rate, the liquid volume and the gas pressure were found to be significantly influencing unlike the surface tension. The validity of the relationships with surfactin fermentations obtained at a larger scale was demonstrated.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
ENSCL
CNRS
INRA
ISA
Univ. Artois
Univ. Littoral Côte d’Opale

Collections :

• BioEcoAgro - UMR-T 1158
• Unité Matériaux et Transformations (UMET) - UMR 8207

Équipe(s) de recherche :

Processus aux Interfaces et Hygiène des Matériaux (PIHM)

Date de dépôt :

2019-05-17T09:25:15Z
2020-12-14T13:30:52Z