Designing clinical trials based on modern ...
Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
PMID :
Permalink :
Title :
Designing clinical trials based on modern imaging and metastasis-directed treatments in patients with oligometastatic breast cancer: a consensus recommendation from the EORTC Imaging and Breast Cancer Groups.
Author(s) :
Pasquier, David [Auteur]
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]
Bidaut, L. [Auteur]
Oprea-Lager, D. E. [Auteur]
Desouza, N. M. [Auteur]
Krug, D. [Auteur]
Collette, L. [Auteur]
Kunz, W. [Auteur]
Belkacemi, Y. [Auteur]
Bau, M. G. [Auteur]
Caramella, C. [Auteur]
De Geus-Oei, L. F. [Auteur]
De Caluwé, A. [Auteur]
Deroose, C. [Auteur]
Gheysens, O. [Auteur]
Herrmann, K. [Auteur]
Kindts, I. [Auteur]
Kontos, M. [Auteur]
Kümmel, S. [Auteur]
Linderholm, B. [Auteur]
Lopci, E. [Auteur]
Meattini, I. [Auteur]
Smeets, A. [Auteur]
Kaidar-Person, O. [Auteur]
Poortmans, P. [Auteur]
Tsoutsou, P. [Auteur]
Hajjaji, Nawale [Auteur]
Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
Russell, N. [Auteur]
Senkus, E. [Auteur]
Talbot, J. N. [Auteur]
Umutlu, L. [Auteur]
Vandecaveye, V. [Auteur]
Verhoeff, J. J. C. [Auteur]
Van Oordt, W. M. H. [Auteur]
Zacho, H. D. [Auteur]
Cardoso, F. [Auteur]
Fournier, L. [Auteur]
Van Duijnhoven, F. [Auteur]
Lecouvet, F. E. [Auteur]
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]
Bidaut, L. [Auteur]
Oprea-Lager, D. E. [Auteur]
Desouza, N. M. [Auteur]
Krug, D. [Auteur]
Collette, L. [Auteur]
Kunz, W. [Auteur]
Belkacemi, Y. [Auteur]
Bau, M. G. [Auteur]
Caramella, C. [Auteur]
De Geus-Oei, L. F. [Auteur]
De Caluwé, A. [Auteur]
Deroose, C. [Auteur]
Gheysens, O. [Auteur]
Herrmann, K. [Auteur]
Kindts, I. [Auteur]
Kontos, M. [Auteur]
Kümmel, S. [Auteur]
Linderholm, B. [Auteur]
Lopci, E. [Auteur]
Meattini, I. [Auteur]
Smeets, A. [Auteur]
Kaidar-Person, O. [Auteur]
Poortmans, P. [Auteur]
Tsoutsou, P. [Auteur]
Hajjaji, Nawale [Auteur]
Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
Russell, N. [Auteur]
Senkus, E. [Auteur]
Talbot, J. N. [Auteur]
Umutlu, L. [Auteur]
Vandecaveye, V. [Auteur]
Verhoeff, J. J. C. [Auteur]
Van Oordt, W. M. H. [Auteur]
Zacho, H. D. [Auteur]
Cardoso, F. [Auteur]
Fournier, L. [Auteur]
Van Duijnhoven, F. [Auteur]
Lecouvet, F. E. [Auteur]
Journal title :
Lancet Oncology
Abbreviated title :
Lancet Oncol
Volume number :
24
Pages :
e331-e343
Publication date :
2023-08-10
ISSN :
1474-5488
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Breast cancer remains the most common cause of cancer death among women. Despite its considerable histological and molecular heterogeneity, those characteristics are not distinguished in most definitions of oligometastatic ...
Show more >Breast cancer remains the most common cause of cancer death among women. Despite its considerable histological and molecular heterogeneity, those characteristics are not distinguished in most definitions of oligometastatic disease and clinical trials of oligometastatic breast cancer. After an exhaustive review of the literature covering all aspects of oligometastatic breast cancer, 35 experts from the European Organisation for Research and Treatment of Cancer Imaging and Breast Cancer Groups elaborated a Delphi questionnaire aimed at offering consensus recommendations, including oligometastatic breast cancer definition, optimal diagnostic pathways, and clinical trials required to evaluate the effect of diagnostic imaging strategies and metastasis-directed therapies. The main recommendations are the introduction of modern imaging methods in metastatic screening for an earlier diagnosis of oligometastatic breast cancer and the development of prospective trials also considering the histological and molecular complexity of breast cancer. Strategies for the randomisation of imaging methods and therapeutic approaches in different subsets of patients are also addressed.Show less >
Show more >Breast cancer remains the most common cause of cancer death among women. Despite its considerable histological and molecular heterogeneity, those characteristics are not distinguished in most definitions of oligometastatic disease and clinical trials of oligometastatic breast cancer. After an exhaustive review of the literature covering all aspects of oligometastatic breast cancer, 35 experts from the European Organisation for Research and Treatment of Cancer Imaging and Breast Cancer Groups elaborated a Delphi questionnaire aimed at offering consensus recommendations, including oligometastatic breast cancer definition, optimal diagnostic pathways, and clinical trials required to evaluate the effect of diagnostic imaging strategies and metastasis-directed therapies. The main recommendations are the introduction of modern imaging methods in metastatic screening for an earlier diagnosis of oligometastatic breast cancer and the development of prospective trials also considering the histological and molecular complexity of breast cancer. Strategies for the randomisation of imaging methods and therapeutic approaches in different subsets of patients are also addressed.Show less >
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Collections :
Submission date :
2023-12-13T03:41:14Z
2024-01-19T11:02:58Z
2024-01-19T11:02:58Z