Impact of Pre-Existing History of Heart ...
Document type :
Article dans une revue scientifique: Article original
DOI :
PMID :
Title :
Impact of Pre-Existing History of Heart Failure on Patient Profile, Therapeutic Management, and Prognosis in Cardiogenic Shock: Insights from the FRENSHOCK Registry
Author(s) :
Schurtz, Guillaume [Auteur]
Institut Coeur Poumon [CHU Lille]
Delmas, Clément [Auteur]
Institut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Fenouillet, Margaux [Auteur]
Institut Coeur Poumon [CHU Lille]
Roubille, François [Auteur]
Hôpital Arnaud de Villeneuve [CHU Montpellier]
Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] [PhyMedExp]
Puymirat, Etienne [Auteur]
Hôpital Européen Georges Pompidou [APHP] [HEGP]
Bonello, Laurent [Auteur]
Mediterranean Association for Research and Studies in Cardiology [MARS cardio]
Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research [C2VN]
Leurent, Guillaume [Auteur]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Verdier, Basile [Auteur]
Institut Coeur Poumon [CHU Lille]
Levy, Bruno [Auteur]
Défaillance Cardiovasculaire Aiguë et Chronique [DCAC]
Service de Réanimation Médicale [CHRU Nancy]
Ternacle, Julien [Auteur]
Hôpital Haut-Lévêque [CHU Bordeaux]
Harbaoui, Brahim [Auteur]
Hôpital de la Croix-Rousse [CHU - HCL]
Centre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé [CREATIS]
Vanzetto, Gerald [Auteur]
Département de cardiologie [CHU de Grenoble]
Radiopharmaceutiques biocliniques [LRB]
Combaret, Nicolas [Auteur]
Service Cardiologie Médicale et Médecine Vasculaire [CHU Clermont-Ferrand]
Lattuca, Benoît [Auteur]
Initial MAnagement and prevention of acute orGan failures IN critically ill patiEnts [IMAGINE]
Hôpital Universitaire Carémeau [Nîmes] [CHU Nîmes]
Bruel, Cedric [Auteur]
Centre hospitalier Saint-Joseph [Paris]
Bourenne, Jeremy [Auteur]
Hôpital de la Timone [CHU - APHM] [TIMONE]
Labbé, Vincent [Auteur]
CHU Tenon [AP-HP]
Henry, Patrick [Auteur]
Marqueurs cardiovasculaires en situation de stress [MASCOT (UMR_S_942 / U942)]
Hôpital Lariboisière-Fernand-Widal [APHP]
Bonnefoy-Cudraz, Éric [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Cardiovasculaire, métabolisme, diabétologie et nutrition [CarMeN]
Lamblin, Nicolas [Auteur]
Institut Coeur Poumon [CHU Lille]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Lemesle, Gilles [Auteur]
Institut Coeur Poumon [CHU Lille]
Alliance française pour les essais cliniques cardio-vasculaires - French Alliance for Cardiovascular Trials [FACT]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 [RNMCD]
Institut Coeur Poumon [CHU Lille]
Delmas, Clément [Auteur]
Institut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Fenouillet, Margaux [Auteur]
Institut Coeur Poumon [CHU Lille]
Roubille, François [Auteur]
Hôpital Arnaud de Villeneuve [CHU Montpellier]
Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] [PhyMedExp]
Puymirat, Etienne [Auteur]
Hôpital Européen Georges Pompidou [APHP] [HEGP]
Bonello, Laurent [Auteur]
Mediterranean Association for Research and Studies in Cardiology [MARS cardio]
Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research [C2VN]
Leurent, Guillaume [Auteur]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Verdier, Basile [Auteur]
Institut Coeur Poumon [CHU Lille]
Levy, Bruno [Auteur]
Défaillance Cardiovasculaire Aiguë et Chronique [DCAC]
Service de Réanimation Médicale [CHRU Nancy]
Ternacle, Julien [Auteur]
Hôpital Haut-Lévêque [CHU Bordeaux]
Harbaoui, Brahim [Auteur]
Hôpital de la Croix-Rousse [CHU - HCL]
Centre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé [CREATIS]
Vanzetto, Gerald [Auteur]
Département de cardiologie [CHU de Grenoble]
Radiopharmaceutiques biocliniques [LRB]
Combaret, Nicolas [Auteur]
Service Cardiologie Médicale et Médecine Vasculaire [CHU Clermont-Ferrand]
Lattuca, Benoît [Auteur]
Initial MAnagement and prevention of acute orGan failures IN critically ill patiEnts [IMAGINE]
Hôpital Universitaire Carémeau [Nîmes] [CHU Nîmes]
Bruel, Cedric [Auteur]
Centre hospitalier Saint-Joseph [Paris]
Bourenne, Jeremy [Auteur]
Hôpital de la Timone [CHU - APHM] [TIMONE]
Labbé, Vincent [Auteur]
CHU Tenon [AP-HP]
Henry, Patrick [Auteur]
Marqueurs cardiovasculaires en situation de stress [MASCOT (UMR_S_942 / U942)]
Hôpital Lariboisière-Fernand-Widal [APHP]
Bonnefoy-Cudraz, Éric [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Cardiovasculaire, métabolisme, diabétologie et nutrition [CarMeN]
Lamblin, Nicolas [Auteur]

Institut Coeur Poumon [CHU Lille]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Lemesle, Gilles [Auteur]

Institut Coeur Poumon [CHU Lille]
Alliance française pour les essais cliniques cardio-vasculaires - French Alliance for Cardiovascular Trials [FACT]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 [RNMCD]
Journal title :
Life
Pages :
1844
Publisher :
MDPI
Publication date :
2022-11-11
ISSN :
2075-1729
English keyword(s) :
Cardiogenic shock heart failure myocardial infarction mechanical circulatory support
Cardiogenic shock
Heart failure
Myocardial infarction
Mechanical circulatory support
Quantum many-body interaction Adaptive denoiser Quantum denoiser Quantum image processing Adaptive transformation
Quantum many-body interaction
Adaptive denoiser
Quantum denoiser
Quantum image processing
Adaptive transformation
Cardiogenic shock
Heart failure
Myocardial infarction
Mechanical circulatory support
Quantum many-body interaction Adaptive denoiser Quantum denoiser Quantum image processing Adaptive transformation
Quantum many-body interaction
Adaptive denoiser
Quantum denoiser
Quantum image processing
Adaptive transformation
HAL domain(s) :
Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire
Informatique [cs]/Imagerie médicale
Physique [physics]/Mécanique [physics]/Biomécanique [physics.med-ph]
Informatique [cs]/Imagerie médicale
Physique [physics]/Mécanique [physics]/Biomécanique [physics.med-ph]
English abstract : [en]
There is a large heterogeneity among patients presenting with cardiogenic shock (CS). It is crucial to better apprehend this heterogeneity in order to adapt treatments and improve prognoses in these severe patients. Notably, ...
Show more >There is a large heterogeneity among patients presenting with cardiogenic shock (CS). It is crucial to better apprehend this heterogeneity in order to adapt treatments and improve prognoses in these severe patients. Notably, the presence (or absence) of a pre-existing history of chronic heart failure (CHF) at time of CS onset may be a significant part of this heterogeneity, and data focusing on this aspect are lacking. We aimed to compare CS patients with new-onset HF to those with worsening CHF in the multicenter FRENSHOCK registry. Altogether, 772 CS patients were prospectively included: 433 with a previous history of CHF and 339 without. Worsening CHF patients were older (68 +/− 13.4 vs. 62.7 +/− 16.2, p < 0.001) and had a greater burden of extra-cardiac comorbidities. At admission, acute myocardial infarction was predominantly observed in the new-onset HF group (49.9% vs. 25.6%, p < 0.001). When focusing on hemodynamic parameters, worsening CHF patients showed more congestion and higher ventricular filling pressures. Worsening CHF patients experienced higher in-hospital all-cause mortality (31.3% vs. 24.2%, p = 0.029). Our results emphasize the great heterogeneity of the patients presenting with CS. Worsening CHF patients had higher risk profiles, and this translated to a 30% increase in in-hospital all-cause mortality. The heterogeneity of this population prompts us to better determine the phenotype of CS patients to adapt their management.Show less >
Show more >There is a large heterogeneity among patients presenting with cardiogenic shock (CS). It is crucial to better apprehend this heterogeneity in order to adapt treatments and improve prognoses in these severe patients. Notably, the presence (or absence) of a pre-existing history of chronic heart failure (CHF) at time of CS onset may be a significant part of this heterogeneity, and data focusing on this aspect are lacking. We aimed to compare CS patients with new-onset HF to those with worsening CHF in the multicenter FRENSHOCK registry. Altogether, 772 CS patients were prospectively included: 433 with a previous history of CHF and 339 without. Worsening CHF patients were older (68 +/− 13.4 vs. 62.7 +/− 16.2, p < 0.001) and had a greater burden of extra-cardiac comorbidities. At admission, acute myocardial infarction was predominantly observed in the new-onset HF group (49.9% vs. 25.6%, p < 0.001). When focusing on hemodynamic parameters, worsening CHF patients showed more congestion and higher ventricular filling pressures. Worsening CHF patients experienced higher in-hospital all-cause mortality (31.3% vs. 24.2%, p = 0.029). Our results emphasize the great heterogeneity of the patients presenting with CS. Worsening CHF patients had higher risk profiles, and this translated to a 30% increase in in-hospital all-cause mortality. The heterogeneity of this population prompts us to better determine the phenotype of CS patients to adapt their management.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
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