γ‐Lactam‐Based Antifungal Compounds against ...
Type de document :
Compte-rendu et recension critique d'ouvrage
DOI :
Titre :
γ‐Lactam‐Based Antifungal Compounds against the Wheat Pathogen Zymoseptoria tritici
Auteur(s) :
Damiens, Audrey [Auteur]
Dascalu, Anca‐elena [Auteur]
JUNIA [JUNIA]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Taghi Alebrahim, Mohammad [Auteur]
Furman, Christophe [Auteur]
Lipka, Emmanuelle [Auteur]
Ghinet, Alina [Auteur]
JUNIA [JUNIA]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Hilbert, Jean-Louis [Auteur]
Siah, Ali [Auteur]
Billamboz, Muriel [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
JUNIA [JUNIA]
Dascalu, Anca‐elena [Auteur]
JUNIA [JUNIA]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Taghi Alebrahim, Mohammad [Auteur]
Furman, Christophe [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Lipka, Emmanuelle [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Ghinet, Alina [Auteur]
![refId](/themes/Mirage2//images/idref.png)
JUNIA [JUNIA]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Hilbert, Jean-Louis [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Siah, Ali [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Billamboz, Muriel [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
JUNIA [JUNIA]
Titre de la revue :
Chemistry and Biodiversity
Éditeur :
Wiley
Date de publication :
2021-09-28
ISSN :
1612-1872
Discipline(s) HAL :
Chimie
Résumé en anglais : [en]
Abstract As new environmentally friendly and effective antifungal agents are deeply needed, efficient ecofriendly strategies were designed to access two series of compounds inspired from natural γ‐lactams. Designed compounds ...
Lire la suite >Abstract As new environmentally friendly and effective antifungal agents are deeply needed, efficient ecofriendly strategies were designed to access two series of compounds inspired from natural γ‐lactams. Designed compounds were fully characterized and evaluated as antifungal candidates against Zymoseptoria tritici , the main pathogen on wheat crops. The targeted derivatives were prepared from natural resources using green solvents, simple procedures, and limited purification steps. These bio‐inspired compounds revealed as good candidates for further development of efficient crop protection products. Indeed, the HIT compounds exhibited IC 50 around 1 μg/mL and were more active than the references tebuconazole and bixafen towards some multidrug‐resistant strains. Two dozen of derivatives have been obtained for each series and allowed to establish early structure‐activity relationships useful for the development of next generation of γ‐lactam derivatives with improved efficacy.Lire moins >
Lire la suite >Abstract As new environmentally friendly and effective antifungal agents are deeply needed, efficient ecofriendly strategies were designed to access two series of compounds inspired from natural γ‐lactams. Designed compounds were fully characterized and evaluated as antifungal candidates against Zymoseptoria tritici , the main pathogen on wheat crops. The targeted derivatives were prepared from natural resources using green solvents, simple procedures, and limited purification steps. These bio‐inspired compounds revealed as good candidates for further development of efficient crop protection products. Indeed, the HIT compounds exhibited IC 50 around 1 μg/mL and were more active than the references tebuconazole and bixafen towards some multidrug‐resistant strains. Two dozen of derivatives have been obtained for each series and allowed to establish early structure‐activity relationships useful for the development of next generation of γ‐lactam derivatives with improved efficacy.Lire moins >
Langue :
Anglais
Vulgarisation :
Non
Collections :
Source :