Transcranial magnetic stimulation and ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Transcranial magnetic stimulation and aging: effects on spatial learning and memory after sleep deprivation in octodon degus
Auteur(s) :
Estrada, C. [Auteur]
Fernandez-Gomez, Francisco-Jose [Auteur]
Lopez, D. [Auteur]
Gonzalez-Cuello, A. [Auteur]
Tunez, I. [Auteur]
Toledo, F. [Auteur]
Blin, Olivier [Auteur]
Bordet, Regis [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Richardson, Jill C. [Auteur]
Fernandez-Villalba, E. [Auteur]
Herrero, Maria T. [Auteur]
Fernandez-Gomez, Francisco-Jose [Auteur]
Lopez, D. [Auteur]
Gonzalez-Cuello, A. [Auteur]
Tunez, I. [Auteur]
Toledo, F. [Auteur]
Blin, Olivier [Auteur]
Bordet, Regis [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Richardson, Jill C. [Auteur]
Fernandez-Villalba, E. [Auteur]
Herrero, Maria T. [Auteur]
Titre de la revue :
Neurobiology of learning and memory
Nom court de la revue :
Neurobiol. Learn. Mem.
Numéro :
125
Pagination :
274-281
Date de publication :
2015-11-01
ISSN :
1074-7427
Mot(s)-clé(s) en anglais :
Transcranial magnetic stimulation (TMS)
Octodon degus
Sleep deprivation
Alzheimer disease
Aging
Octodon degus
Sleep deprivation
Alzheimer disease
Aging
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
The benefits of neuromodulatory procedures as a possible therapeutic application for cognitive rehabilitation have increased with the progress made in non-invasive modes of brain stimulation in aged-related disorders. ...
Lire la suite >The benefits of neuromodulatory procedures as a possible therapeutic application for cognitive rehabilitation have increased with the progress made in non-invasive modes of brain stimulation in aged-related disorders. Transcranial magnetic stimulation (TMS) is a non-invasive method used to examine multiple facets of the human brain and to ameliorate the impairment in cognition caused by Alzheimer's disease (AD). The present study was designed to evaluate how a chronic TMS treatment could improve learning and memory functions after sleep deprivation (SD) in old Octodon degus. SD was executed by gently handling to keep the animals awake throughout the night. Thirty young and twenty-four old O. degus females were divided in six groups (control, acute and chronic TMS treatment). Behavioral tests included; Radial Arm Maze (RAM), Barnes Maze (BM) and Novel Object Recognition (NOR). Although learning and memory functions improved in young animals with only one session of TMS treatment, a significant improvement in cognitive performance was seen in old animals after 4 and 7days of TMS, depending on the task that was performed. No side effects were observed following, which showed therapeutic potential for improving age-related cognitive performance.Lire moins >
Lire la suite >The benefits of neuromodulatory procedures as a possible therapeutic application for cognitive rehabilitation have increased with the progress made in non-invasive modes of brain stimulation in aged-related disorders. Transcranial magnetic stimulation (TMS) is a non-invasive method used to examine multiple facets of the human brain and to ameliorate the impairment in cognition caused by Alzheimer's disease (AD). The present study was designed to evaluate how a chronic TMS treatment could improve learning and memory functions after sleep deprivation (SD) in old Octodon degus. SD was executed by gently handling to keep the animals awake throughout the night. Thirty young and twenty-four old O. degus females were divided in six groups (control, acute and chronic TMS treatment). Behavioral tests included; Radial Arm Maze (RAM), Barnes Maze (BM) and Novel Object Recognition (NOR). Although learning and memory functions improved in young animals with only one session of TMS treatment, a significant improvement in cognitive performance was seen in old animals after 4 and 7days of TMS, depending on the task that was performed. No side effects were observed following, which showed therapeutic potential for improving age-related cognitive performance.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Équipe(s) de recherche :
Troubles cognitifs dégénératifs et vasculaires
Date de dépôt :
2019-11-27T13:36:30Z