Transcatheter aortic valve replacement ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Transcatheter aortic valve replacement with early- and new-generation devices in bicuspid aortic valve stenosis
Auteur(s) :
Yoon, Sung-Han [Auteur]
Lefevre, Thierry [Auteur]
Ahn, Jung-Ming [Auteur]
Perlman, Gidon Y. [Auteur]
Dvir, Danny [Auteur]
Latib, Azeem [Auteur]
Barbanti, Marco [Auteur]
Deuschl, Florian [Auteur]
De Backer, Ole [Auteur]
Blanke, Philipp [Auteur]
Modine, Thomas [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Pache, Gregor [Auteur]
Neumann, Franz-Josef [Auteur]
Ruile, Philipp [Auteur]
Arai, Takahide [Auteur]
Ohno, Yohei [Auteur]
Kaneko, Hidehiro [Auteur]
Tay, Edgar [Auteur]
Schofer, Niklas [Auteur]
Holy, Erik W. [Auteur]
Luk, Ngai H V. [Auteur]
Yong, Gerald [Auteur]
Lu, Qingsheng [Auteur]
Kong, William K F. [Auteur]
Hon, Jimmy [Auteur]
Kao, Hsien-Li [Auteur]
Lee, Michael [Auteur]
Yin, Wei-Hsian [Auteur]
Park, Duk-Woo [Auteur]
Kang, Soo-Jin [Auteur]
Lee, Seung-Whan [Auteur]
Kim, Young-Hak [Auteur]
Lee, Cheol Whan [Auteur]
Park, Seong-Wook [Auteur]
Kim, Hyo-Soo [Auteur]
Butter, Christian [Auteur]
Khalique, Omar K. [Auteur]
Schaefer, Ulrich [Auteur]
Nietlispach, Fabian [Auteur]
Kodali, Susheel K. [Auteur]
Leon, Martin B. [Auteur]
Ye, Jian [Auteur]
Chevalier, Bernard [Auteur]
Leipsic, Jonathon [Auteur]
Delgado, Victoria [Auteur]
Bax, Jeroen J. [Auteur]
Tamburino, Corrado [Auteur]
Colombo, Antonio [Auteur]
Sondergaard, Lars [Auteur]
Webb, John G. [Auteur]
Park, Seung-Jung [Auteur]
Lefevre, Thierry [Auteur]
Ahn, Jung-Ming [Auteur]
Perlman, Gidon Y. [Auteur]
Dvir, Danny [Auteur]
Latib, Azeem [Auteur]
Barbanti, Marco [Auteur]
Deuschl, Florian [Auteur]
De Backer, Ole [Auteur]
Blanke, Philipp [Auteur]
Modine, Thomas [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Pache, Gregor [Auteur]
Neumann, Franz-Josef [Auteur]
Ruile, Philipp [Auteur]
Arai, Takahide [Auteur]
Ohno, Yohei [Auteur]
Kaneko, Hidehiro [Auteur]
Tay, Edgar [Auteur]
Schofer, Niklas [Auteur]
Holy, Erik W. [Auteur]
Luk, Ngai H V. [Auteur]
Yong, Gerald [Auteur]
Lu, Qingsheng [Auteur]
Kong, William K F. [Auteur]
Hon, Jimmy [Auteur]
Kao, Hsien-Li [Auteur]
Lee, Michael [Auteur]
Yin, Wei-Hsian [Auteur]
Park, Duk-Woo [Auteur]
Kang, Soo-Jin [Auteur]
Lee, Seung-Whan [Auteur]
Kim, Young-Hak [Auteur]
Lee, Cheol Whan [Auteur]
Park, Seong-Wook [Auteur]
Kim, Hyo-Soo [Auteur]
Butter, Christian [Auteur]
Khalique, Omar K. [Auteur]
Schaefer, Ulrich [Auteur]
Nietlispach, Fabian [Auteur]
Kodali, Susheel K. [Auteur]
Leon, Martin B. [Auteur]
Ye, Jian [Auteur]
Chevalier, Bernard [Auteur]
Leipsic, Jonathon [Auteur]
Delgado, Victoria [Auteur]
Bax, Jeroen J. [Auteur]
Tamburino, Corrado [Auteur]
Colombo, Antonio [Auteur]
Sondergaard, Lars [Auteur]
Webb, John G. [Auteur]
Park, Seung-Jung [Auteur]
Titre de la revue :
Journal of the American College of Cardiology
Nom court de la revue :
J. Am. Coll. Cardiol.
Numéro :
68
Pagination :
1195-1205
Date de publication :
2016-09-01
ISSN :
0735-1097
Mot(s)-clé(s) en anglais :
paravalvular leak
mortality
new device
mortality
new device
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Few studies have evaluated the clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve stenosis (AS). Particularly, limited data exist comparing the results of TAVR with ...
Lire la suite >Few studies have evaluated the clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve stenosis (AS). Particularly, limited data exist comparing the results of TAVR with new-generation devices versus early-generation devices. This study sought to evaluate the clinical outcomes of TAVR for bicuspid AS with early- and new-generation devices. The Bicuspid TAVR Registry is an international multicenter study enrolling consecutive patients with bicuspid AS undergoing TAVR between April 2005 and May 2015. Of 301 patients, 199 patients (71.1%) were treated with early-generation devices (Sapien XT [Edwards Lifesciences Corporation, Irvine, California]: n = 87; CoreValve [Medtronic, Minneapolis, Minnesota]: n = 112) and 102 with new-generation devices (Sapien 3 [Edwards Lifesciences Corporation]: n = 91; Lotus [Boston Scientific Corporation, Marlborough, Massachusetts]: n = 11). The mean Society of Thoracic Surgeons score was 4.7 ± 5.2 without significant differences between groups (4.6 ± 5.1 vs. 4.9 ± 5.4; p = 0.57). Overall, all-cause mortality rates were 4.3% at 30 days and 14.4% at 1 year. Moderate or severe paravalvular leak was absent and significantly less frequent with new-generation compared to early-generation devices (0.0% vs. 8.5%; p = 0.002), which resulted in a higher device success rate (92.2% vs. 80.9%; p = 0.01). There were no differences between early- and new-generation devices in stroke (2.5% vs. 2.0%; p > 0.99), life-threatening bleeding (3.5% vs. 2.9%; p > 0.99), major vascular complication (4.5% vs. 2.9%; p = 0.76), stage 2 to 3 acute kidney injury (2.5% vs. 2.9%; p > 0.99), early safety endpoints (15.1% vs. 10.8%; p = 0.30), and 30-day all-cause mortality (4.5% vs. 3.9%; p > 0.99). The clinical outcomes of TAVR in patients with bicuspid AS were favorable. New-generation devices were associated with less paravalvular leak and, hence, a higher device success rate than early-generation devices. (The Bicuspid Aortic Stenosis Following Transcatheter Aortic Valve Replacement Registry [Bicuspid TAVR]; NCT02394184).Lire moins >
Lire la suite >Few studies have evaluated the clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve stenosis (AS). Particularly, limited data exist comparing the results of TAVR with new-generation devices versus early-generation devices. This study sought to evaluate the clinical outcomes of TAVR for bicuspid AS with early- and new-generation devices. The Bicuspid TAVR Registry is an international multicenter study enrolling consecutive patients with bicuspid AS undergoing TAVR between April 2005 and May 2015. Of 301 patients, 199 patients (71.1%) were treated with early-generation devices (Sapien XT [Edwards Lifesciences Corporation, Irvine, California]: n = 87; CoreValve [Medtronic, Minneapolis, Minnesota]: n = 112) and 102 with new-generation devices (Sapien 3 [Edwards Lifesciences Corporation]: n = 91; Lotus [Boston Scientific Corporation, Marlborough, Massachusetts]: n = 11). The mean Society of Thoracic Surgeons score was 4.7 ± 5.2 without significant differences between groups (4.6 ± 5.1 vs. 4.9 ± 5.4; p = 0.57). Overall, all-cause mortality rates were 4.3% at 30 days and 14.4% at 1 year. Moderate or severe paravalvular leak was absent and significantly less frequent with new-generation compared to early-generation devices (0.0% vs. 8.5%; p = 0.002), which resulted in a higher device success rate (92.2% vs. 80.9%; p = 0.01). There were no differences between early- and new-generation devices in stroke (2.5% vs. 2.0%; p > 0.99), life-threatening bleeding (3.5% vs. 2.9%; p > 0.99), major vascular complication (4.5% vs. 2.9%; p = 0.76), stage 2 to 3 acute kidney injury (2.5% vs. 2.9%; p > 0.99), early safety endpoints (15.1% vs. 10.8%; p = 0.30), and 30-day all-cause mortality (4.5% vs. 3.9%; p > 0.99). The clinical outcomes of TAVR in patients with bicuspid AS were favorable. New-generation devices were associated with less paravalvular leak and, hence, a higher device success rate than early-generation devices. (The Bicuspid Aortic Stenosis Following Transcatheter Aortic Valve Replacement Registry [Bicuspid TAVR]; NCT02394184).Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Équipe(s) de recherche :
Troubles cognitifs dégénératifs et vasculaires
Date de dépôt :
2019-11-27T14:34:11Z