Symptomatic patients remain at substantial ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Symptomatic patients remain at substantial risk of arterial disease complications before and after endarterectomy or stenting
Auteur(s) :
Hobeanu, Cristina [Auteur]
Lavallee, Philippa C. [Auteur]
Rothwell, Peter M. [Auteur]
Sissani, Leila [Auteur]
Albers, Gregory W. [Auteur]
Bornstein, Natan M. [Auteur]
Caplan, Louis R. [Auteur]
Donnan, Geoffrey A. [Auteur]
Ferro, Jose M. [Auteur]
Hennerici, Michael G. [Auteur]
Labreuche, Julien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Molina, Carlos [Auteur]
Steg, Philippe Gabriel [Auteur]
Touboul, Pierre-Jean [Auteur]
Uchiyama, Shinichiro [Auteur]
Vicaut, Eric [Auteur]
Wong, Lawrence K S. [Auteur]
Amarenco, Pierre [Auteur]
Lavallee, Philippa C. [Auteur]
Rothwell, Peter M. [Auteur]
Sissani, Leila [Auteur]
Albers, Gregory W. [Auteur]
Bornstein, Natan M. [Auteur]
Caplan, Louis R. [Auteur]
Donnan, Geoffrey A. [Auteur]
Ferro, Jose M. [Auteur]
Hennerici, Michael G. [Auteur]
Labreuche, Julien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Molina, Carlos [Auteur]
Steg, Philippe Gabriel [Auteur]
Touboul, Pierre-Jean [Auteur]
Uchiyama, Shinichiro [Auteur]
Vicaut, Eric [Auteur]
Wong, Lawrence K S. [Auteur]
Amarenco, Pierre [Auteur]
Titre de la revue :
Stroke
Nom court de la revue :
Stroke
Numéro :
48
Pagination :
1005-1010
Date de publication :
2017-04-01
ISSN :
0039-2499
Mot(s)-clé(s) en anglais :
prevention
transient ischemic attack
carotid arteries
carotid endarterectomy
myocardial infarction
transient ischemic attack
carotid arteries
carotid endarterectomy
myocardial infarction
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
After carotid endarterectomy (CEA) or carotid artery stenting (CAS) in patients with transient ischemic attack or minor ischemic stroke, recurrent stroke risk falls to a low rate on modern medical treatment.
We used data ...
Lire la suite >After carotid endarterectomy (CEA) or carotid artery stenting (CAS) in patients with transient ischemic attack or minor ischemic stroke, recurrent stroke risk falls to a low rate on modern medical treatment. We used data from 4583 patients with recent transient ischemic attack or minor stroke enrolled in the TIAregistry.org to perform a nested case-control analysis to evaluate pre- and post-CEA/CAS risk. Cases were defined as patients with a CEA/CAS during the 1-year follow-up period. For each case, 2 controls with a follow-up time greater than the time from qualifying event to CEA/CAS were randomly selected, matched by age and sex. Primary outcome was defined as major vascular events (MVE, including stroke, cardiovascular death, and myocardial infarction). The median delay from symptom onset of qualifying event to CEA/CAS was 11 days (interquartile range, 6-23). Overall, patients with CEA/CAS had a higher 1-year risk of MVE than other patients (14.8% versus 5.8%; adjusted hazard ratio, 2.40; 95% confidence interval, 1.61-3.60; PPP Patients with CEA/CAS had a higher 12-month risk of MVE, as well as during pre- and postprocedural periods. These results suggest that patients in whom CEA/CAS is anticipated are likely to be an informative population for inclusion in studies testing new antithrombotic strategies started soon after symptom onset.Lire moins >
Lire la suite >After carotid endarterectomy (CEA) or carotid artery stenting (CAS) in patients with transient ischemic attack or minor ischemic stroke, recurrent stroke risk falls to a low rate on modern medical treatment. We used data from 4583 patients with recent transient ischemic attack or minor stroke enrolled in the TIAregistry.org to perform a nested case-control analysis to evaluate pre- and post-CEA/CAS risk. Cases were defined as patients with a CEA/CAS during the 1-year follow-up period. For each case, 2 controls with a follow-up time greater than the time from qualifying event to CEA/CAS were randomly selected, matched by age and sex. Primary outcome was defined as major vascular events (MVE, including stroke, cardiovascular death, and myocardial infarction). The median delay from symptom onset of qualifying event to CEA/CAS was 11 days (interquartile range, 6-23). Overall, patients with CEA/CAS had a higher 1-year risk of MVE than other patients (14.8% versus 5.8%; adjusted hazard ratio, 2.40; 95% confidence interval, 1.61-3.60; PPP Patients with CEA/CAS had a higher 12-month risk of MVE, as well as during pre- and postprocedural periods. These results suggest that patients in whom CEA/CAS is anticipated are likely to be an informative population for inclusion in studies testing new antithrombotic strategies started soon after symptom onset.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Université de Lille
Université de Lille
Date de dépôt :
2019-12-09T18:16:14Z