Title :

Clinical significance of isolated atypical transient symptoms in a cohort with transient ischemic attack

Author(s) :

Lavallee, Philippa C. [Auteur]
Sissani, Leila [Auteur]
Labreuche, Julien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Meseguer, Elena [Auteur]
Cabrejo, Lucie [Auteur]
Guidoux, Céline [Auteur]
Klein, Isabelle F. [Auteur]
Touboul, Pierre-Jean [Auteur]
Amarenco, Pierre [Auteur]

Journal title :

Stroke

Abbreviated title :

Stroke

Volume number :

48

Pages :

1495-+

Publication date :

2017-06-01

ISSN :

0039-2499

English keyword(s) :

infarction
ischemic attack
transient
vertigo
prevalence
embolism

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Contrary to typical transient symptoms (TS), atypical TS, such as partial sensory deficit, dysarthria, vertigo/unsteadiness, unusual cortical visual deficit, and diplopia, are not usually classified as symptoms of transient ...
Show more >Contrary to typical transient symptoms (TS), atypical TS, such as partial sensory deficit, dysarthria, vertigo/unsteadiness, unusual cortical visual deficit, and diplopia, are not usually classified as symptoms of transient ischemic attack when they occur in isolation, and their clinical relevance is frequently denied. Consecutive patients with recent TS admitted in our transient ischemic attack clinic (2003-2008) had systematic brain, arterial, and cardiac investigations. We compared the prevalence of recent infarction on brain imaging, major investigational findings (symptomatic intracranial or extracranial atherosclerotic stenosis ≥50%, cervical arterial dissection, and major source of cardiac embolism), and 1-year risk of major vascular events in patients with isolated typical or atypical TS and nonisolated TS, after exclusion of the main differential diagnoses. Among 1850 patients with possible or definite ischemic diagnoses, 798 (43.1%) had isolated TS: 621 (33.6%) typical and 177 (9.6%) atypical. Acute infarction on brain imaging was similar in patients with isolated atypical and typical TS but less frequent than in patients with nonisolated TS, observed in 10.0%, 11.5%, and 15.3%, respectively (PP Transient ischemic attack diagnosis should be considered and investigated in patients with isolated atypical TS.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2019-12-09T18:16:27Z