Designing specific cheese-ripening ecosystems ...
Type de document :
Compte-rendu et recension critique d'ouvrage
Titre :
Designing specific cheese-ripening ecosystems to shape the immune effects of dairy products?
Auteur(s) :
Ple, Coline [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Adouard, Nadège [Auteur]
Génie et Microbiologie des Procédés Alimentaires [GMPA]
Breton, Jérôme [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Deuiulf, Joelle [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Pot, Bruno [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Bonnarme, Pascal [Auteur]
Génie et Microbiologie des Procédés Alimentaires [GMPA]
Foligné, Benoit [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Adouard, Nadège [Auteur]
Génie et Microbiologie des Procédés Alimentaires [GMPA]
Breton, Jérôme [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Deuiulf, Joelle [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Pot, Bruno [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Bonnarme, Pascal [Auteur]
Génie et Microbiologie des Procédés Alimentaires [GMPA]
Foligné, Benoit [Auteur]
Lactic Acid Bacteria & Mucosal Immunity - CIIL
Titre de la revue :
journal of functional foods
Pagination :
219 - 229
Éditeur :
Elsevier
Date de publication :
2015
ISSN :
1756-4646
Mot(s)-clé(s) en anglais :
Smear-cheese microflora
PBMC
Immunomodulation
Colitis
Mouse model
INFLAMMATORY-BOWEL-DISEASE
LACTIC-ACBACTERIA
REGULATORY T-CELLS
IN-VITRO
EXPERIMENTAL COLITIS
BIFIDOBACTERIUM STRAINS
GUT MICROBIOTA
PROBIOTICS
MECHANISMS
MODEL
PBMC
Immunomodulation
Colitis
Mouse model
INFLAMMATORY-BOWEL-DISEASE
LACTIC-ACBACTERIA
REGULATORY T-CELLS
IN-VITRO
EXPERIMENTAL COLITIS
BIFIDOBACTERIUM STRAINS
GUT MICROBIOTA
PROBIOTICS
MECHANISMS
MODEL
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Although large numbers of viable microorganisms are ingested in ripened cheese, little is known about the microbial ecosystems' influence on the host's immune responses. We designed experimental smear-ripened cheeses with ...
Lire la suite >Although large numbers of viable microorganisms are ingested in ripened cheese, little is known about the microbial ecosystems' influence on the host's immune responses. We designed experimental smear-ripened cheeses with bacteria and yeasts that have opposite immune effects and evaluated their impact in the dextran sulphate sodium (DSS) and trinitrobenzene sulphonic acid (TNBS) colitis mouse models. Mice were fed with a control diet, a milk matrix or with lab-designed, 28-day-ripened prototype soft cheeses A and B (CheA and CheB) from cow milk that respectively hosted consortia of immuno-enhancing and immuno-modulatory microbial strains. Inflammatory markers and transcriptional signatures were evaluated in healthy mice colitic mice. In the DSS colitis model, there were no differences between CheA and CheB in terms of the inflammatory read-outs. In contrast, CheA (but not CheB) exacerbated weight loss and colon lesions in the TNBS model suggesting that designer cheeses may provide opportunities for diet management. (C) 2014 Elsevier Ltd. All rights reserved.Lire moins >
Lire la suite >Although large numbers of viable microorganisms are ingested in ripened cheese, little is known about the microbial ecosystems' influence on the host's immune responses. We designed experimental smear-ripened cheeses with bacteria and yeasts that have opposite immune effects and evaluated their impact in the dextran sulphate sodium (DSS) and trinitrobenzene sulphonic acid (TNBS) colitis mouse models. Mice were fed with a control diet, a milk matrix or with lab-designed, 28-day-ripened prototype soft cheeses A and B (CheA and CheB) from cow milk that respectively hosted consortia of immuno-enhancing and immuno-modulatory microbial strains. Inflammatory markers and transcriptional signatures were evaluated in healthy mice colitic mice. In the DSS colitis model, there were no differences between CheA and CheB in terms of the inflammatory read-outs. In contrast, CheA (but not CheB) exacerbated weight loss and colon lesions in the TNBS model suggesting that designer cheeses may provide opportunities for diet management. (C) 2014 Elsevier Ltd. All rights reserved.Lire moins >
Langue :
Anglais
Vulgarisation :
Non
Source :
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- https://doi.org/10.1016/j.jff.2014.11.021
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