Chemical structure and biological activity ...
Type de document :
Compte-rendu et recension critique d'ouvrage
Titre :
Chemical structure and biological activity of a highly branched (1 → 3,1 → 6)-D-glucan from <i>Isochrysis galbana</i>
Auteur(s) :
Sadovskaya, Irina [Auteur]
Biochimie des Produits Aquatiques [BPA]
Souissi, Anissa [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Souissi, Sami [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Grard, Thierry [Auteur]
Biochimie des Produits Aquatiques [BPA]
Lencel, Philippe [Auteur]
Biochimie des Produits Aquatiques [BPA]
M. Greene, Catherine [Auteur]
Duin, Sarah [Auteur]
Dmitrenok, Pavel S. [Auteur]
Chizhov, Alexander O. [Auteur]
Shashkov, Alexander S. [Auteur]
Usov, Anatolii I. [Auteur]
Biochimie des Produits Aquatiques [BPA]
Souissi, Anissa [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Souissi, Sami [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Grard, Thierry [Auteur]
Biochimie des Produits Aquatiques [BPA]
Lencel, Philippe [Auteur]
Biochimie des Produits Aquatiques [BPA]
M. Greene, Catherine [Auteur]
Duin, Sarah [Auteur]
Dmitrenok, Pavel S. [Auteur]
Chizhov, Alexander O. [Auteur]
Shashkov, Alexander S. [Auteur]
Usov, Anatolii I. [Auteur]
Titre de la revue :
Carbohydrate Polymers
Pagination :
139-148
Éditeur :
Elsevier
Date de publication :
2014
ISSN :
0144-8617
Discipline(s) HAL :
Planète et Univers [physics]/Sciences de la Terre/Océanographie
Résumé en anglais : [en]
tA highly branched (1 → 3,1 → 6)- -d-glucan was isolated from the microalga Isochrysis galbana Parke(Isochrysidales, Haptophyta). The polysaccharide structure was analyzed by methylation and Smithdegradation, as well as ...
Lire la suite >tA highly branched (1 → 3,1 → 6)- -d-glucan was isolated from the microalga Isochrysis galbana Parke(Isochrysidales, Haptophyta). The polysaccharide structure was analyzed by methylation and Smithdegradation, as well as by ESI and MALDI TOF mass spectrometry and NMR spectroscopy. The glucanwas shown to contain a (1 → 6)-linked backbone, where every residue is substituted at position 3 byGlc, which in turn may be substituted at C-6 by a single Glc or by rather short (up to tetrasaccharide)oligosaccharide chains. All the 3-linked Glc residues are present in these side chains. In the biologicalactivity experiments it was demonstrated that the polysaccharide directly inhibits the proliferation ofU937 human leukemic monocyte lymphoma cells and therefore has potential anti-tumor activity.Lire moins >
Lire la suite >tA highly branched (1 → 3,1 → 6)- -d-glucan was isolated from the microalga Isochrysis galbana Parke(Isochrysidales, Haptophyta). The polysaccharide structure was analyzed by methylation and Smithdegradation, as well as by ESI and MALDI TOF mass spectrometry and NMR spectroscopy. The glucanwas shown to contain a (1 → 6)-linked backbone, where every residue is substituted at position 3 byGlc, which in turn may be substituted at C-6 by a single Glc or by rather short (up to tetrasaccharide)oligosaccharide chains. All the 3-linked Glc residues are present in these side chains. In the biologicalactivity experiments it was demonstrated that the polysaccharide directly inhibits the proliferation ofU937 human leukemic monocyte lymphoma cells and therefore has potential anti-tumor activity.Lire moins >
Langue :
Anglais
Vulgarisation :
Non
Source :