Economic burden in non-Hodgkin lymphoma ...
Document type :
Article dans une revue scientifique: Article original
DOI :
PMID :
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Title :
Economic burden in non-Hodgkin lymphoma survivors: The French Lymphoma Study Association SIMONAL cross-sectional study.
Author(s) :
Nerich, V. [Auteur]
Centre Hospitalier Régional Universitaire de Besançon [CHRU Besançon]
Guyeux, C. [Auteur]
Henry-Amar, M. [Auteur]
Couturier, R. [Auteur]
Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) [FEMTO-ST]
Thieblemont, C. [Auteur]
Ribrag, V. [Auteur]
Tilly, H. [Auteur]
Haioun, C. [Auteur]
Casasnovas, R. O. [Auteur]
Morschhauser, Franck [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Feugier, P. [Auteur]
Sibon, D. [Auteur]
Ysebaert, L. [Auteur]
Nicolas-Virelizier, E. [Auteur]
Broussais-Guillaumot, F. [Auteur]
Damaj, G. L. [Auteur]
Jais, J. P. [Auteur]
Salles, G. [Auteur]
Service d’Hématologie [Centre Hospitalier Lyon Sud - HCL]
Woronoff-Lemsi, M. [Auteur]
Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098) [RIGHT]
Mounier, N. [Auteur]
Centre Hospitalier Régional Universitaire de Besançon [CHRU Besançon]
Guyeux, C. [Auteur]
Henry-Amar, M. [Auteur]
Couturier, R. [Auteur]
Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) [FEMTO-ST]
Thieblemont, C. [Auteur]
Ribrag, V. [Auteur]
Tilly, H. [Auteur]
Haioun, C. [Auteur]
Casasnovas, R. O. [Auteur]
Morschhauser, Franck [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Feugier, P. [Auteur]
Sibon, D. [Auteur]
Ysebaert, L. [Auteur]
Nicolas-Virelizier, E. [Auteur]
Broussais-Guillaumot, F. [Auteur]
Damaj, G. L. [Auteur]
Jais, J. P. [Auteur]
Salles, G. [Auteur]
Service d’Hématologie [Centre Hospitalier Lyon Sud - HCL]
Woronoff-Lemsi, M. [Auteur]
Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098) [RIGHT]
Mounier, N. [Auteur]
Journal title :
Cancer
Volume number :
128
Pages :
519-528
Publication date :
2021-10-04
ISSN :
1097-0142
Keyword(s) :
rituximab
non-Hodgkin lymphoma
health care resource use
health care cost
explanatory factors
cancer survivors
non-Hodgkin lymphoma
health care resource use
health care cost
explanatory factors
cancer survivors
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Background
No study has focused on the economic burden in non-Hodgkin lymphoma (NHL) survivors, even though this knowledge is essential. This study reports on health care resource use and associated health care costs ...
Show more >Background No study has focused on the economic burden in non-Hodgkin lymphoma (NHL) survivors, even though this knowledge is essential. This study reports on health care resource use and associated health care costs as well as related factors in a series of 1671 French long-term NHL survivors. Methods Health care costs were measured from the payer perspective. Only direct medical costs (medical consultations, outpatient treatments, hospitalizations, and medical transport) in the past 12 months were included (reference year 2015). Multiple linear regression was used to search for explanatory factors of health care costs. Results In total, 1100 survivors (66%) reported having used at least 1 health care resource, and 867 (52%) reported having used at least 1 outpatient treatment. After the authors accounted for missing data, the mean health care cost was estimated at €702 ± €2221. Hospitalizations and outpatient treatments were the main cost drivers. Sensitivity analyses confirmed the robustness of the results. For the 1100 survivors who reported using at least 1 health care resource, the mean health care cost was €1067 ± €2268. Several factors demonstrated statistically significant relationships with health care costs. For instance, cardiovascular disorders increased costs by 66% ± 16%. In contrast, rituximab or autologous stem cell transplantation as initial therapy had no effect on health care costs. Conclusions The consideration of economic constraints in health care is now a reality. This retrospective study reports on a better understanding of health care resource use and associated health care costs as well as related factors. It may help health care professionals in their ongoing efforts to design person-centered health care pathways.Show less >
Show more >Background No study has focused on the economic burden in non-Hodgkin lymphoma (NHL) survivors, even though this knowledge is essential. This study reports on health care resource use and associated health care costs as well as related factors in a series of 1671 French long-term NHL survivors. Methods Health care costs were measured from the payer perspective. Only direct medical costs (medical consultations, outpatient treatments, hospitalizations, and medical transport) in the past 12 months were included (reference year 2015). Multiple linear regression was used to search for explanatory factors of health care costs. Results In total, 1100 survivors (66%) reported having used at least 1 health care resource, and 867 (52%) reported having used at least 1 outpatient treatment. After the authors accounted for missing data, the mean health care cost was estimated at €702 ± €2221. Hospitalizations and outpatient treatments were the main cost drivers. Sensitivity analyses confirmed the robustness of the results. For the 1100 survivors who reported using at least 1 health care resource, the mean health care cost was €1067 ± €2268. Several factors demonstrated statistically significant relationships with health care costs. For instance, cardiovascular disorders increased costs by 66% ± 16%. In contrast, rituximab or autologous stem cell transplantation as initial therapy had no effect on health care costs. Conclusions The consideration of economic constraints in health care is now a reality. This retrospective study reports on a better understanding of health care resource use and associated health care costs as well as related factors. It may help health care professionals in their ongoing efforts to design person-centered health care pathways.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
Submission date :
2023-05-25T02:57:09Z
2023-07-12T10:41:04Z
2023-07-12T10:41:04Z