Prevalence of post-acute COVID-19 symptoms ...
Document type :
Article dans une revue scientifique: Article original
PMID :
Permalink :
Title :
Prevalence of post-acute COVID-19 symptoms twelve months after hospitalisation in participants retained in follow-up: analyses stratified by gender from a large prospective cohort.
Author(s) :
Ghosn, J. [Auteur]
Bachelet, D. [Auteur]
Livrozet, M. [Auteur]
Cervantes-Gonzalez, M. [Auteur]
Poissy, Julien [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle (UGSF) - UMR 8576
Goehringer, F. [Auteur]
Gandonniere, C. S. [Auteur]
Maillet, M. [Auteur]
Bani-Sadr, F. [Auteur]
Martin-Blondel, G. [Auteur]
Tattevin, P. [Auteur]
Launay, O. [Auteur]
Surgers, L. [Auteur]
Dudoignon, E. [Auteur]
Liegeon, G. [Auteur]
Zucman, D. [Auteur]
Joseph, C. [Auteur]
Senneville, Eric [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Yelnik, Cécile [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Roger, P. M. [Auteur]
Faure, Karine [Auteur]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
Gousseff, M. [Auteur]
Cabie, A. [Auteur]
Duval, X. [Auteur]
Chirouze, C. [Auteur]
Laouenan, Cédric [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Bachelet, D. [Auteur]
Livrozet, M. [Auteur]
Cervantes-Gonzalez, M. [Auteur]
Poissy, Julien [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle (UGSF) - UMR 8576
Goehringer, F. [Auteur]
Gandonniere, C. S. [Auteur]
Maillet, M. [Auteur]
Bani-Sadr, F. [Auteur]
Martin-Blondel, G. [Auteur]
Tattevin, P. [Auteur]
Launay, O. [Auteur]
Surgers, L. [Auteur]
Dudoignon, E. [Auteur]
Liegeon, G. [Auteur]
Zucman, D. [Auteur]
Joseph, C. [Auteur]
Senneville, Eric [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Yelnik, Cécile [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Roger, P. M. [Auteur]
Faure, Karine [Auteur]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
Gousseff, M. [Auteur]
Cabie, A. [Auteur]
Duval, X. [Auteur]
Chirouze, C. [Auteur]
Laouenan, Cédric [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Journal title :
Clinical Microbiology and Infection
Abbreviated title :
Clin Microbiol Infect
Volume number :
29
Pages :
254.E7-254.E13
Publisher :
Elsevier
Publication date :
2022-10-04
ISSN :
1469-0691
English keyword(s) :
Cohort
Emerging infectious diseases
Moderate to severe COVID-19
Post-acute COVID-19 symptoms
SARS-CoV-2
Emerging infectious diseases
Moderate to severe COVID-19
Post-acute COVID-19 symptoms
SARS-CoV-2
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Objectives
Persistent post-acute coronavirus disease 2019 (COVID-19) symptoms (PACSs) have been reported up to 6 months after hospital discharge. Herein we assessed the symptoms that persisted 12 months (M12) after admission ...
Show more >Objectives Persistent post-acute coronavirus disease 2019 (COVID-19) symptoms (PACSs) have been reported up to 6 months after hospital discharge. Herein we assessed the symptoms that persisted 12 months (M12) after admission for COVID-19 in the longitudinal prospective national French coronavirus disease cohort. Methods Hospitalized patients with a confirmed virological diagnosis of COVID-19 were enrolled. Follow-up was planned until M12 after admission. Associations between persistence of ≥3 PACSs at M12 and clinical characteristics at admission were assessed through logistic regression according to gender. Results We focused on participants enrolled between 24 January 2020 and 15 July 2020, to allow M12 follow-up. The M12 data were available for 737 participants. Median age was 61 years, 475 (64%) were men and 242/647 (37%) were admitted to intensive care units during the acute phase. At M12, 27% (194/710) of the participants had ≥3 persistent PACS, mostly fatigue, dyspnoea and joint pain. Among those who had a professional occupation before the acute phase, 91 out of 339 (27%) were still on sick leave at M12. Presence of ≥3 persistent PACS was associated with female gender, both anxiety and depression, impaired health-related quality of life and Medical Muscle Research Council Scale <57. Compared with men, women more often reported presence of ≥3 persistent PACSs (98/253, 39% vs. 96/457, 21%), depression and anxiety (18/152, 12% vs. 17/268, 6% and 33/156, 21% vs. 26/264, 10%, respectively), impaired physical health-related quality of life (76/141, 54% vs. 120/261, 46%). Women had less often returned to work than men (77/116, 66% vs. 171/223, 77%). Conclusions One fourth of the individuals admitted to hospital for COVID-19 still had ≥3 persistent PACSs at M12 post-discharge. Women reported more often ≥3 persistent PACSs, suffered more from anxiety and depression and had less often returned to work than men.Show less >
Show more >Objectives Persistent post-acute coronavirus disease 2019 (COVID-19) symptoms (PACSs) have been reported up to 6 months after hospital discharge. Herein we assessed the symptoms that persisted 12 months (M12) after admission for COVID-19 in the longitudinal prospective national French coronavirus disease cohort. Methods Hospitalized patients with a confirmed virological diagnosis of COVID-19 were enrolled. Follow-up was planned until M12 after admission. Associations between persistence of ≥3 PACSs at M12 and clinical characteristics at admission were assessed through logistic regression according to gender. Results We focused on participants enrolled between 24 January 2020 and 15 July 2020, to allow M12 follow-up. The M12 data were available for 737 participants. Median age was 61 years, 475 (64%) were men and 242/647 (37%) were admitted to intensive care units during the acute phase. At M12, 27% (194/710) of the participants had ≥3 persistent PACS, mostly fatigue, dyspnoea and joint pain. Among those who had a professional occupation before the acute phase, 91 out of 339 (27%) were still on sick leave at M12. Presence of ≥3 persistent PACS was associated with female gender, both anxiety and depression, impaired health-related quality of life and Medical Muscle Research Council Scale <57. Compared with men, women more often reported presence of ≥3 persistent PACSs (98/253, 39% vs. 96/457, 21%), depression and anxiety (18/152, 12% vs. 17/268, 6% and 33/156, 21% vs. 26/264, 10%, respectively), impaired physical health-related quality of life (76/141, 54% vs. 120/261, 46%). Women had less often returned to work than men (77/116, 66% vs. 171/223, 77%). Conclusions One fourth of the individuals admitted to hospital for COVID-19 still had ≥3 persistent PACSs at M12 post-discharge. Women reported more often ≥3 persistent PACSs, suffered more from anxiety and depression and had less often returned to work than men.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Submission date :
2023-11-15T03:16:04Z
2024-05-15T09:58:11Z
2024-05-15T09:58:11Z