Rationale and design of ePPOP-ID: a ...
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Title :
Rationale and design of ePPOP-ID: a multicenter randomized controlled trial using an electronic-personalized program for obesity in pregnancy to improve delivery.
Author(s) :
Deruelle, Philippe [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Lelorain, Sophie [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Deghilage, Sylvie [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Couturier, Emmanuelle [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Guilbert, Elodie [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Berveiller, Paul [Auteur]
Service de gynécologie et obstétrique [CHI Poissy-Saint Germain]
Sénat, Marie Victoire [Auteur]
Vayssière, Christophe [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Sentilhes, Loïc [Auteur]
Centre Hospitalier Universitaire de Bordeaux [CHU de Bordeaux]
Perrotin, Franck [Auteur]
Imaging, Brain & Neuropsychiatry [iBraiN]
Gallot, Denis [Auteur]
Retinoids, Development and Developmental Diseases [R2D2]
Chauleur, Cécile [Auteur]
Université Jean Monnet - Saint-Étienne [UJM]
Sananes, Nicolas [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Roth, Emmanuel [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Luton, Dominique [Auteur]
Service de Gynécologie - Obstétrique [CHU Bichat]
Caputo, Marie [Auteur]
Centre Hospitalier de Lens
Lorio, Elodie [Auteur]
Centre hospitalier [Valenciennes, Nord]
Chatelet, Carla [Auteur]
Couster, Julien [Auteur]
Centre Hospitalier Boulogne-sur-mer
Timbely, Oumar [Auteur]
Centre Hospitalier de Meaux
Doret-Dion, Muriel [Auteur]
Hôpital Femme Mère Enfant [CHU - HCL] [HFME]
Duhamel, Alain [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Pigeyre, Marie [Auteur]
Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 [EGENODIA (GI3M)]
Environnement périnatal et croissance - EA 4489 [EPS]
Lelorain, Sophie [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Deghilage, Sylvie [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Couturier, Emmanuelle [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Guilbert, Elodie [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Berveiller, Paul [Auteur]
Service de gynécologie et obstétrique [CHI Poissy-Saint Germain]
Sénat, Marie Victoire [Auteur]
Vayssière, Christophe [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Sentilhes, Loïc [Auteur]
Centre Hospitalier Universitaire de Bordeaux [CHU de Bordeaux]
Perrotin, Franck [Auteur]
Imaging, Brain & Neuropsychiatry [iBraiN]
Gallot, Denis [Auteur]
Retinoids, Development and Developmental Diseases [R2D2]
Chauleur, Cécile [Auteur]
Université Jean Monnet - Saint-Étienne [UJM]
Sananes, Nicolas [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Roth, Emmanuel [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Luton, Dominique [Auteur]
Service de Gynécologie - Obstétrique [CHU Bichat]
Caputo, Marie [Auteur]
Centre Hospitalier de Lens
Lorio, Elodie [Auteur]
Centre hospitalier [Valenciennes, Nord]
Chatelet, Carla [Auteur]
Couster, Julien [Auteur]
Centre Hospitalier Boulogne-sur-mer
Timbely, Oumar [Auteur]
Centre Hospitalier de Meaux
Doret-Dion, Muriel [Auteur]
Hôpital Femme Mère Enfant [CHU - HCL] [HFME]
Duhamel, Alain [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Pigeyre, Marie [Auteur]
Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 [EGENODIA (GI3M)]
Journal title :
BMC Pregnancy and Childbirth
Abbreviated title :
BMC Pregnancy Childbirth
Volume number :
20
Pages :
602
Publication date :
2020-10-10
ISSN :
1471-2393
English keyword(s) :
Obesity
Pregnancy
Cesarean delivery
Instrumental delivery
Physical activity
Nutrition
Fetus
Macrosomia
Pregnancy
Cesarean delivery
Instrumental delivery
Physical activity
Nutrition
Fetus
Macrosomia
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Background
Pre-pregnancy obesity and excessive gestational weight gain (GWG) are established risk factors for adverse pregnancy, delivery and birth outcomes. Pregnancy is an ideal moment for nutritional interventions ...
Show more >Background Pre-pregnancy obesity and excessive gestational weight gain (GWG) are established risk factors for adverse pregnancy, delivery and birth outcomes. Pregnancy is an ideal moment for nutritional interventions in order to establish healthier lifestyle behaviors in women at high risk of obstetric and neonatal complications. Methods Electronic-Personalized Program for Obesity during Pregnancy to Improve Delivery (ePPOP-ID) is an open multicenter randomized controlled trial which will assess the efficacy of an e-health web-based platform offering a personalized lifestyle program to obese pregnant women in order to reduce the rate of labor procedures and delivery interventions in comparison to standard care. A total of 860 eligible pregnant women will be recruited in 18 centers in France between 12 and 22 weeks of gestation, randomized into the intervention or the control arm and followed until 10 weeks of postpartum. The intervention is based on nutrition, eating behavior, physical activity, motivation and well-being advices in which personalization is central, as well as the use of a mobile/tablet application. Inputs includes data from the medical record of participants (medical history, anthropometric data), from the web platform (questionnaires on dietary habits, eating behavior, physical activity and motivation in both groups), and adherence to the program (time of connection for the intervention group only). Data are collected at inclusion, 32 weeks, delivery and 10 weeks postpartum. As primary outcome, we will use a composite endpoint score of obstetrical interventions during labor and delivery, defined as caesarean section and instrumental delivery (forceps and vacuum extractor). Secondary outcomes will consist of data routinely collected as part of usual antenatal and perinatal care, such as GWG, hypertension, preeclampsia, as well as fetal and neonatal outcomes including premature birth, gestational age at birth, birth weight, macrosomia, Apgar score, arterial umbilical cord pH, neonatal traumatism, hyperbilirubinemia, respiratory distress syndrome, transfer in neonatal intensive care unit, and neonatal adiposity. Post-natal outcomes will be duration of breastfeeding, maternal weight retention and child weight at postnatal visit. Discussion The findings of the ePPOP-ID trial will help design e-health intervention program for obese women in pregnancy. Trial registration ClinicalTrials.gov Identifier: NCT02924636 / October 5th 2016.Show less >
Show more >Background Pre-pregnancy obesity and excessive gestational weight gain (GWG) are established risk factors for adverse pregnancy, delivery and birth outcomes. Pregnancy is an ideal moment for nutritional interventions in order to establish healthier lifestyle behaviors in women at high risk of obstetric and neonatal complications. Methods Electronic-Personalized Program for Obesity during Pregnancy to Improve Delivery (ePPOP-ID) is an open multicenter randomized controlled trial which will assess the efficacy of an e-health web-based platform offering a personalized lifestyle program to obese pregnant women in order to reduce the rate of labor procedures and delivery interventions in comparison to standard care. A total of 860 eligible pregnant women will be recruited in 18 centers in France between 12 and 22 weeks of gestation, randomized into the intervention or the control arm and followed until 10 weeks of postpartum. The intervention is based on nutrition, eating behavior, physical activity, motivation and well-being advices in which personalization is central, as well as the use of a mobile/tablet application. Inputs includes data from the medical record of participants (medical history, anthropometric data), from the web platform (questionnaires on dietary habits, eating behavior, physical activity and motivation in both groups), and adherence to the program (time of connection for the intervention group only). Data are collected at inclusion, 32 weeks, delivery and 10 weeks postpartum. As primary outcome, we will use a composite endpoint score of obstetrical interventions during labor and delivery, defined as caesarean section and instrumental delivery (forceps and vacuum extractor). Secondary outcomes will consist of data routinely collected as part of usual antenatal and perinatal care, such as GWG, hypertension, preeclampsia, as well as fetal and neonatal outcomes including premature birth, gestational age at birth, birth weight, macrosomia, Apgar score, arterial umbilical cord pH, neonatal traumatism, hyperbilirubinemia, respiratory distress syndrome, transfer in neonatal intensive care unit, and neonatal adiposity. Post-natal outcomes will be duration of breastfeeding, maternal weight retention and child weight at postnatal visit. Discussion The findings of the ePPOP-ID trial will help design e-health intervention program for obese women in pregnancy. Trial registration ClinicalTrials.gov Identifier: NCT02924636 / October 5th 2016.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
Submission date :
2023-11-15T08:01:51Z
2023-12-21T14:35:31Z
2024-02-20T15:34:09Z
2023-12-21T14:35:31Z
2024-02-20T15:34:09Z
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