Acquired von Willebrand Syndrome in Patients ...
Document type :
Compte-rendu et recension critique d'ouvrage
DOI :
Title :
Acquired von Willebrand Syndrome in Patients With Ventricular Assist Device
Author(s) :
Rauch, Antoine [Auteur]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 [RNMCD]
Susen, Sophie [Auteur]
Zieger, Barbara [Auteur]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 [RNMCD]
Susen, Sophie [Auteur]
Zieger, Barbara [Auteur]
Journal title :
Frontiers in Medicine
Publisher :
Frontiers media
Publication date :
2019-02-05
ISSN :
2296-858X
English keyword(s) :
ventricular assist devices von Willebrand factor acquired von Willebrand syndrome ECMO bleeding
ventricular assist devices
von Willebrand factor
acquired von Willebrand syndrome
ECMO
bleeding
ventricular assist devices
von Willebrand factor
acquired von Willebrand syndrome
ECMO
bleeding
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
During the last decade the use of ventricular assist devices (VADs) for patients with severe heart failure has increased tremendously. However, flow disturbances, mainly high shear induced by the device is associated with ...
Show more >During the last decade the use of ventricular assist devices (VADs) for patients with severe heart failure has increased tremendously. However, flow disturbances, mainly high shear induced by the device is associated with bleeding complications. Shear stress-induced changes in VWF conformation are associated with a loss of high molecular weight multimers (HMW) of VWF and an increased risk of bleeding. This phenomenon and its cause will be elaborated and reviewed in the following.Show less >
Show more >During the last decade the use of ventricular assist devices (VADs) for patients with severe heart failure has increased tremendously. However, flow disturbances, mainly high shear induced by the device is associated with bleeding complications. Shear stress-induced changes in VWF conformation are associated with a loss of high molecular weight multimers (HMW) of VWF and an increased risk of bleeding. This phenomenon and its cause will be elaborated and reviewed in the following.Show less >
Language :
Anglais
Popular science :
Non
Source :
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