Title :

Technical development and feasibility of a reusable vest to integrate cardiovascular magnetic resonance with electrocardiographic imaging.

Author(s) :

Webber, M. [Auteur]
Joy, G. [Auteur]
Bennett, J. [Auteur]
Chan, F. [Auteur]
Falconer, D. [Auteur]
Shiwani, H. [Auteur]
Davies, R. H. [Auteur]
Krausz, G. [Auteur]
Tanackovic, S. [Auteur]
Guger, C. [Auteur]
Gonzalez, P. [Auteur]
Martin, E. [Auteur]
Wong, A. [Auteur]
Rapala, A. [Auteur]
Direk, K. [Auteur]
Kellman, P. [Auteur]
Pierce, I. [Auteur]
Rudy, Y. [Auteur]
Vijayakumar, R. [Auteur]
Chaturvedi, N. [Auteur]
Hughes, A. D. [Auteur]
Moon, J. C. [Auteur]
Lambiase, P. D. [Auteur]
Tao, Xuyuan [Auteur]
École nationale supérieure des arts et industries textiles [ENSAIT]
Koncar, Vladan [Auteur]
École nationale supérieure des arts et industries textiles [ENSAIT]
Orini, M. [Auteur]
Captur, G. [Auteur]

Journal title :

Journal of Cardiovascular Magnetic Resonance

Abbreviated title :

J Cardiovasc Magn Reson

Volume number :

25

Pages :

73

Publication date :

2023-12-05

ISSN :

1532-429X

English keyword(s) :

Cardiovascular magnetic resonance imaging
Electrocardiographic imaging
Electrophysiology
Feasibility
Reproducibility

HAL domain(s) :

Sciences de l'ingénieur [physics]

English abstract : [en]

Background Electrocardiographic imaging (ECGI) generates electrophysiological (EP) biomarkers while cardiovascular magnetic resonance (CMR) imaging provides data about myocardial structure, function and tissue substrate. ...
Show more >Background Electrocardiographic imaging (ECGI) generates electrophysiological (EP) biomarkers while cardiovascular magnetic resonance (CMR) imaging provides data about myocardial structure, function and tissue substrate. Combining this information in one examination is desirable but requires an affordable, reusable, and high-throughput solution. We therefore developed the CMR-ECGI vest and carried out this technical development study to assess its feasibility and repeatability in vivo. Methods CMR was prospectively performed at 3T on participants after collecting surface potentials using the locally designed and fabricated 256-lead ECGI vest. Epicardial maps were reconstructed to generate local EP parameters such as activation time (AT), repolarization time (RT) and activation recovery intervals (ARI). 20 intra- and inter-observer and 8 scan re-scan repeatability tests. Results 77 participants were recruited: 27 young healthy volunteers (HV, 38.9 ± 8.5 years, 35% male) and 50 older persons (77.0 ± 0.1 years, 52% male). CMR-ECGI was achieved in all participants using the same reusable, washable vest without complications. Intra- and inter-observer variability was low (correlation coefficients [rs] across unipolar electrograms = 0.99 and 0.98 respectively) and scan re-scan repeatability was high (rs between 0.81 and 0.93). Compared to young HV, older persons had significantly longer RT (296.8 vs 289.3 ms, p = 0.002), ARI (249.8 vs 235.1 ms, p = 0.002) and local gradients of AT, RT and ARI (0.40 vs 0.34 ms/mm, p = 0,01; 0.92 vs 0.77 ms/mm, p = 0.03; and 1.12 vs 0.92 ms/mm, p = 0.01 respectively). Conclusion Our high-throughput CMR-ECGI solution is feasible and shows good reproducibility in younger and older participants. This new technology is now scalable for high throughput research to provide novel insights into arrhythmogenesis and potentially pave the way for more personalised risk stratification.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
ENSAIT
Junia HEI

Collections :

• Génie des matériaux textiles (GEMTEX) - ULR 2641

Submission date :

2024-03-27T22:02:25Z
2024-10-01T13:10:13Z