Bioinformatics tools to analyse non-ribosomal ...
Type de document :
Autre communication scientifique (congrès sans actes - poster - séminaire...): Communication dans un congrès avec actes: Conférence invitée
Titre :
Bioinformatics tools to analyse non-ribosomal peptides and other metabolites
Auteur(s) :
Pupin, Maude [Auteur]
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]
Titre de la manifestation scientifique :
Symposium Natural Products (Meta)Genome Mining
Organisateur(s) de la manifestation scientifique :
Novo Nordisk Foundation Science Cluster
Ville :
Copenhagen
Pays :
Danemark
Date de début de la manifestation scientifique :
2022-05-30
Mot(s)-clé(s) en anglais :
non-ribosomal peptides
metabolites
Computational biology and chemistry
metabolites
Computational biology and chemistry
Discipline(s) HAL :
Chimie/Chemo-informatique
Informatique [cs]/Bio-informatique [q-bio.QM]
Informatique [cs]/Bio-informatique [q-bio.QM]
Résumé en anglais : [en]
Secondary metabolites are in between small molecules and sequences, as they are composed by monomers (amino acids, sugars, lipids, etc.) but are not always linear. We design a specific notation to describe the monomeric ...
Lire la suite >Secondary metabolites are in between small molecules and sequences, as they are composed by monomers (amino acids, sugars, lipids, etc.) but are not always linear. We design a specific notation to describe the monomeric structure: a graph in which the nodes are the monomers and the edges are the chemical bonds between them (ex: peptide bonds). This notation helps linking a metabolite to its biosynthetic gene cluster, when its synthesis is an assembly of monomers. We conceived tools to analyse and visualize secondary metabolites, based on this notation. s2m and rBAN infer a monomeric structure from a chemical structure. Kendrick Formula Predictor and NRPro help analysing mass spectrometry results. And Norine is a database dedicated to non-ribosomal peptides. It can be queried by annotations or monomeric structures. https://bioinfo.cristal.univ-lille.fr/NRP/Lire moins >
Lire la suite >Secondary metabolites are in between small molecules and sequences, as they are composed by monomers (amino acids, sugars, lipids, etc.) but are not always linear. We design a specific notation to describe the monomeric structure: a graph in which the nodes are the monomers and the edges are the chemical bonds between them (ex: peptide bonds). This notation helps linking a metabolite to its biosynthetic gene cluster, when its synthesis is an assembly of monomers. We conceived tools to analyse and visualize secondary metabolites, based on this notation. s2m and rBAN infer a monomeric structure from a chemical structure. Kendrick Formula Predictor and NRPro help analysing mass spectrometry results. And Norine is a database dedicated to non-ribosomal peptides. It can be queried by annotations or monomeric structures. https://bioinfo.cristal.univ-lille.fr/NRP/Lire moins >
Langue :
Anglais
Comité de lecture :
Non
Audience :
Internationale
Vulgarisation :
Non
Collections :
Source :