Titre :

Effects of microplastics on the kidneys: A narrative review

Auteur(s) :

Bueno de Oliveira, Rodrigo [Auteur]
Universidade Estadual de Campinas = University of Campinas [UNICAMP]
Pelepenko, Lauter [Auteur]
Universidade Estadual de Campinas = University of Campinas [UNICAMP]
Masaro, Daniela [Auteur]
Universidade Estadual de Campinas = University of Campinas [UNICAMP]
Lustosa, Glauco M.M. M. [Auteur]
Cassani, Mariana [Auteur]
Universidade Estadual de Campinas = University of Campinas [UNICAMP]
Roza, Noemí A.V. [Auteur]
Universidade Estadual de Campinas = University of Campinas [UNICAMP]
Marciano, Marina [Auteur]
Universidade Estadual de Campinas = University of Campinas [UNICAMP]
dos Reis, Luciene [Auteur]
Universidade de São Paulo = University of São Paulo [USP]
Kamel, Saïd [Auteur]
Laboratoire de Biochimie [CHU Amiens]
Mécanismes physiopathologiques et conséquences des calcifications cardiovasculaires - UR UPJV 7517 [MP3CV]
Louvet, Loïc [Auteur]
Mécanismes physiopathologiques et conséquences des calcifications cardiovasculaires - UR UPJV 7517 [MP3CV]
Marrow Adiposity & Bone Lab - Adiposité Médullaire et Os - ULR 4490 [MABLab]
Mazon., Talita [Auteur]

Titre de la revue :

Kidney International

Pagination :

400-407

Éditeur :

Nature Publishing Group

Date de publication :

2024-06

ISSN :

0085-2538

Mot(s)-clé(s) en anglais :

chronic kidney disease
kidney
microplastics

Discipline(s) HAL :

Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Urologie et Néphrologie

Résumé en anglais : [en]

Micro- and nanoplastics (MPs) are small synthetic organic polymer particles (<5 mm and <1 μm, respectively) that originate directly from plastic compounds or result from the degradation of plastic. These particles ...
Lire la suite >Micro- and nanoplastics (MPs) are small synthetic organic polymer particles (<5 mm and <1 μm, respectively) that originate directly from plastic compounds or result from the degradation of plastic. These particles are a global concern since they are widely distributed in water, air, food and soil, and recent scientific evidence has linked MPs to negative biological effects. Although these particles are difficult to detect in humans, MPs have been identified in different biological fluids and tissues, such as the placenta, lung, intestines, liver, blood, urine, and kidneys. Human exposure to MPs can occur by ingestion, inhalation, or dermal contact, potentially causing metabolic alterations. Data from experimental and clinical studies have revealed that the ability of MPs to promote inflammation, oxidative stress, and organ dysfunction and negatively affect clinical outcomes is associated with their accumulation in body fluids and tissues. Although evidence of the putative action of MPs in the human kidney is still scarce, there is growing interest in studying MPs in this organ. In addition, chronic kidney disease (CKD) requires investigation because this condition is potentially prone to MP accumulation. The purpose of the present article is (i) to review the general aspects of MP generation, available analytic methods for identification and the main known biological toxic effects and (ii) to describe and critically analyze key experimental and clinical studies that support a role of MPs in kidney disease.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Collections :

• Marrow Adiposity & Bone Lab (MABLab) - ULR 4490

Source :

Harvested from HAL