MPAgenomics : An R package for multi-patients ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
Titre :
MPAgenomics : An R package for multi-patients analysis of genomic markers
Auteur(s) :
Grimonprez, Quentin [Auteur]
MOdel for Data Analysis and Learning [MODAL]
Celisse, Alain [Auteur]
Laboratoire Paul Painlevé - UMR 8524 [LPP]
MOdel for Data Analysis and Learning [MODAL]
Blanck, Samuel [Auteur]
MOdel for Data Analysis and Learning [MODAL]
Cheok, Meyling [Auteur]
Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 [JPArc]
Figeac, Martin [Auteur]
Plateforme de génomique fonctionnelle et structurelle [Lille]
Briend, Guillemette [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
MOdel for Data Analysis and Learning [MODAL]
MOdel for Data Analysis and Learning [MODAL]
Celisse, Alain [Auteur]
Laboratoire Paul Painlevé - UMR 8524 [LPP]
MOdel for Data Analysis and Learning [MODAL]
Blanck, Samuel [Auteur]
MOdel for Data Analysis and Learning [MODAL]
Cheok, Meyling [Auteur]

Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 [JPArc]
Figeac, Martin [Auteur]

Plateforme de génomique fonctionnelle et structurelle [Lille]
Briend, Guillemette [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
MOdel for Data Analysis and Learning [MODAL]
Titre de la revue :
BMC Bioinformatics
Pagination :
394
Éditeur :
BioMed Central
Date de publication :
2014-12
ISSN :
1471-2105
Mot(s)-clé(s) en anglais :
segmentation
normalization
calling
genomic markers selection
SNP array
multi patient analysis
normalization
calling
genomic markers selection
SNP array
multi patient analysis
Discipline(s) HAL :
Sciences du Vivant [q-bio]/Bio-Informatique, Biologie Systémique [q-bio.QM]
Résumé en anglais : [en]
MPAgenomics, standing for multi-patients analysis (MPA) of genomic markers, is an R-package devoted to: (i) efficient segmentation, and (ii) genomic marker selection from multi-patient copy number and SNP data profiles. ...
Lire la suite >MPAgenomics, standing for multi-patients analysis (MPA) of genomic markers, is an R-package devoted to: (i) efficient segmentation, and (ii) genomic marker selection from multi-patient copy number and SNP data profiles. It provides wrappers from commonly used packages to facilitate their repeated (sometimes difficult) use, offering an easy-to-use pipeline for beginners in R. The segmentation of successive multiple profiles (finding losses and gains) is based on a new automatic choice of influential parameters since default ones were misleading in the original packages. Considering multiple profiles in the same time, MPAgenomics wraps efficient penalized regression methods to select relevant markers associated with a given response.Lire moins >
Lire la suite >MPAgenomics, standing for multi-patients analysis (MPA) of genomic markers, is an R-package devoted to: (i) efficient segmentation, and (ii) genomic marker selection from multi-patient copy number and SNP data profiles. It provides wrappers from commonly used packages to facilitate their repeated (sometimes difficult) use, offering an easy-to-use pipeline for beginners in R. The segmentation of successive multiple profiles (finding losses and gains) is based on a new automatic choice of influential parameters since default ones were misleading in the original packages. Considering multiple profiles in the same time, MPAgenomics wraps efficient penalized regression methods to select relevant markers associated with a given response.Lire moins >
Langue :
Anglais
Comité de lecture :
Oui
Audience :
Internationale
Vulgarisation :
Non
Collections :
Source :
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