Title :

Diaphragmatic weakness related to radiotherapy: 2 cases and a review

Author(s) :

Davion, Jean Baptiste [Auteur]
Service de neurologie et pathologie du mouvement
Centre de référence des maladies rares neuromusculaires
Duthoit, Louise [Auteur]
Service de Pneumologie et Immuno-Allergologie [CHU LIlle]
Centre de référence des maladies rares neuromusculaires
Starzyńska-Kubicka, Aleksandra [Auteur]
Medical University of Warsaw - Poland
Perez, Thierry [Auteur]
Centre de référence des maladies rares neuromusculaires
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Bocquillon, Perrine [Auteur]
Service de neurophysiologie clinique [CHRU Lille]
Defebvre, Luc [Auteur]
Service de neurologie et pathologie du mouvement
Nguyen The Tich, Sylvie [Auteur]
Centre de référence des maladies rares neuromusculaires
Lefebvre, Guillaume [Auteur]
Radiologie et Imagerie Musculo-Squelettique [CHU Lille]
Tard, Celine [Auteur]
Service de neurologie et pathologie du mouvement
Centre de référence des maladies rares neuromusculaires

Journal title :

REVUE NEUROLOGIQUE

Pages :

796-801

Publisher :

Elsevier Masson

Publication date :

2022-10-01

ISSN :

0035-3787

English keyword(s) :

Magnetic resonance imaging
Electrodiagnosis
Radiation
Radiotherapy
Respiratory failure

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Post-radiation diaphragmatic weakness have rarely been described. We report two cases of post-radiation diaphragmatic weakness from our center, and review the other published cases, computing clinical, electromyography and ...
Show more >Post-radiation diaphragmatic weakness have rarely been described. We report two cases of post-radiation diaphragmatic weakness from our center, and review the other published cases, computing clinical, electromyography and magnetic resonance imaging data. Including our two cases, seven cases of post-radiation diaphragmatic weakness have been described. Most occurred after mantle-field radiotherapy for Hodgkin lymphoma (5/7), often in associations with chemotherapy (4/7). Other radiations-induced complications were found (5/7) such as brachial plexopathy, cardiac involvement or hypothyroidy. When studied, phrenic nerve conduction studies revealed different profiles, from clearly abnormal responses to limit amplitudes. Imaging can be a useful diagnostic tool, displaying abnormalities with sharp limits matching the radiation field. Data is limited about long-term evolution. Presentation of post-radiation diaphragmatic weakness seems relatively homogeneous. We propose a diagnosis work-up for post-radiation diaphragmatic weakness, to exclude potentially treatable differential diagnoses.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Collections :

• Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017

Source :

Harvested from HAL

Submission date :

2025-02-19T03:55:01Z