Title :

Effect of pesticide and sprouting inhibitor on potato crops on gut microbiota and hepatic gene expression in mice

Author(s) :

Theysgeur, Sandy [Auteur]
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
BioEcoAgro - Equipe 7 - Health benefit of protein hydrolysates and agro-food co-products: control of production, characterization and valorisation
Dugardin, Camille [Auteur]
BioEcoAgro - Equipe 7 - Health benefit of protein hydrolysates and agro-food co-products: control of production, characterization and valorisation
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
Lemiere, Sébastien [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Université de Lille
Hilbert, Jean-Louis [Auteur]
Stress Abiotiques et Diffenciation des Végétaux Cultivés [Stress Abiotiques]
Stress Abiotiques et Différenciation des Végétaux Cultivés [SADV]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Institut Charles Viollette (ICV) - ULR 7394 [ICV]
BioEcoAgro - Equipe 5 - Specialized Metabolites of Plant Origin
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
Siah, Ali [Auteur]
BioEcoAgro - Equipe 5 - Specialized Metabolites of Plant Origin
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
JUNIA [JUNIA]
Ravallec, Rozenn [Auteur]
BioEcoAgro - Equipe 7 - Health benefit of protein hydrolysates and agro-food co-products: control of production, characterization and valorisation
Laboratoire de Technologie des Substances Naturelles [LTSN]
Procédés Biologiques, Génie Enzymatique et Microbien - EA1026 [ProBioGEM]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
Lucau-Danila, Anca [Auteur]
BioEcoAgro - Equipe 5 - Specialized Metabolites of Plant Origin

Conference title :

8th International Conference on FOOD DIGESTION

City :

Porto

Country :

Portugal

Start date of the conference :

2024-04-09

English keyword(s) :

Potato
Gut microbiota
Gene expression
Health
Pesticide mixtures

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Purpose: The widespread consumption of potatoes is attributed to their easy availability and affordability. While potatoes providenumerous benefits, concerns arise due to their high carbohydrate content, often associated ...
Show more >Purpose: The widespread consumption of potatoes is attributed to their easy availability and affordability. While potatoes providenumerous benefits, concerns arise due to their high carbohydrate content, often associated with health issues like obesity anddiabetes. Nevertheless, they are rich in health-promoting compounds such as ascorbic acid, vitamins (C, B3, B6), proteins, minerals,and dietary fibers. Resistant starch, found in potatoes, acts as a beneficial nutrient for the gut microbiome. However, pesticides arecommonly used during potato crop cultivation to combat diseases like mildew. Additionally, sprouting inhibitor treatments areemployed for extended potato storage. Despite the known health hazards associated with pesticides, limited research has beenexamined on the combined effect of pesticide mixtures within food matrices. This study aims to explore the influence of pesticidetreatments during crop cultivation and sprouting inhibitor treatments during storage, on the gut microbiota population and hepaticgene expression.Methods: Lyophilized bio or conventional potato with or without sprouting treatment or water was administered through orogastricgavage in mice over a 3-week period. Then, mice were euthanized to collect organs like the liver. Feces were collected before theinitial gavage and after 3 weeks of gavage. Nutrigenomic analysis was conducted on liver RNA, and metagenomic analysis wasperformed on feces.Results: Findings from this study demonstrated notable modifications in gut microbiota and liver gene expression in mice followingthe consumption of potato bio or conventional, with or without storage (sprouting inhibitor treatment).Conclusion: This study highlights the effect of pesticide treatment and storage of potato on both gut microbiota population andgene expression modulation in the liver.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515

Source :

Harvested from HAL