Title :

Structural Transformations of <scp>d</scp> -Mannitol Induced by in Situ Milling Using Real Time Powder Synchrotron Radiation Diffraction

Author(s) :

Martinetto, Pauline [Auteur]
Matériaux, Rayonnements, Structure [NEEL - MRS]
Bordet, Pierre [Auteur]
Matériaux, Rayonnements, Structure [NEEL - MRS]
Descamps, Marc [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Dudognon, Emeline [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Pagnoux, William [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Willart, Jean-François [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]

Journal title :

Crystal Growth & Design

Volume number :

17

Pages :

6111-6122

Publication date :

2017-10-06

HAL domain(s) :

Physique [physics]/Matière Condensée [cond-mat]/Systèmes désordonnés et réseaux de neurones [cond-mat.dis-nn]
Physique [physics]/Matière Condensée [cond-mat]/Science des matériaux [cond-mat.mtrl-sci]
Physique [physics]/Matière Condensée [cond-mat]/Matière Molle [cond-mat.soft]

English abstract : [en]

We have investigated the solid-state transformation of anhydrous β-d-mannitol upon milling using synchrotron X-ray powder diffraction. The 1720 diffraction patterns, collected in real time during the operation of the mill ...
Show more >We have investigated the solid-state transformation of anhydrous β-d-mannitol upon milling using synchrotron X-ray powder diffraction. The 1720 diffraction patterns, collected in real time during the operation of the mill (6 h), have been analyzed by sequential Rietveld refinements. From this analysis we confirm that a polymorphic conversion has occurred from the form β toward the form α. Moreover, the quantification and the microstructural analysis of both polymorphs have allowed obtaining new results: (i) the kinetic of the transformation is characterized by a sigmoidal shape, (ii) little microstructural evolution occurs during the solid-state transformation, (iii) no intermediate amorphous phase, preceding the transformation toward the metastable crystalline α phase, can be detected. A comparison in depth of the two crystal structures is given, and two models are proposed in order to explain this direct conversion β → α.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
ENSCL
CNRS
INRA

Collections :

• Unité Matériaux et Transformations (UMET) - UMR 8207

Research team(s) :

Matériaux Moléculaires et Thérapeutiques

Submission date :

2019-10-30T15:38:14Z
2024-09-10T14:07:26Z