Hematoma location and morphology of anticoagulation-associated intracerebral hemorrhage

Seiffge, David J.; Curtze, Sami; Dequatre-Ponchelle, Nelly; Pezzini, Alessandro; Tatlisumak, Turgut; Cordonnier, Charlotte; Werring, David J.

Type de document :

Article dans une revue scientifique: Article original

DOI :

10.1212/WNL.0000000000006958

PMID :

30674603

URL permanente :

http://hdl.handle.net/20.500.12210/16103

Titre :

Hematoma location and morphology of anticoagulation-associated intracerebral hemorrhage

Auteur(s) :

Seiffge, David J. [Auteur]
Curtze, Sami [Auteur]
Dequatre-Ponchelle, Nelly [Auteur]
Pezzini, Alessandro [Auteur]
Tatlisumak, Turgut [Auteur]
Cordonnier, Charlotte [Auteur]

Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Werring, David J. [Auteur]

Titre de la revue :

Neurology

Nom court de la revue :

Neurology

Date de publication :

2019-01-23

ISSN :

1526-632X

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

To study hematoma location and morphology of intracerebral hemorrhage (ICH) associated with oral anticoagulants (OAC) and delineate causes and mechanism. We performed a systematic literature research and meta-analysis of ...
Lire la suite >To study hematoma location and morphology of intracerebral hemorrhage (ICH) associated with oral anticoagulants (OAC) and delineate causes and mechanism. We performed a systematic literature research and meta-analysis of studies comparing neuroimaging findings in patients with OAC-ICH compared to those with ICH not associated with OAC (non-OAC ICH). We calculated pooled risk ratios (RRs) for ICH location using the Mantel-Haenszel random-effects method and corresponding 95% confidence intervals (95% CI). We identified 8 studies including 6,259 patients (OAC-ICH n = 1,107, pooled OAC-ICH population 17.7%). There was some evidence for deep ICH location (defined as ICH in the thalamus, basal ganglia, internal capsule, or brainstem) being less frequent in patients with OAC-ICH (OAC-ICH: 450 of 1,102/40.8% vs non-OAC ICH: 2,656 of 4,819/55.1%; RR 0.94, 95% CI 0.88-1.00, pI 2pI 2pI 2ppI 2ppI 2 The overrepresentation of cerebellar ICH location and intraventricular extension in OAC-ICH might have mechanistic relevance for the underlying arteriopathy, pathophysiology, or bleeding pattern of OAC-ICH, and should be investigated further.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

Lille Neurosciences & Cognition (LilNCog) - U 1172

Équipe(s) de recherche :

Troubles cognitifs dégénératifs et vasculaires

Date de dépôt :

2019-11-27T13:33:29Z

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