2d harmonic filtering of mr phase images ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
2d harmonic filtering of mr phase images in multicenter clinical setting: toward a magnetic signature of cerebral microbleeds
Auteur(s) :
Kaaouana, Takoua [Auteur]
Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM]
Sorbonne Université [SU]
De Rochefort, Ludovic [Auteur]
Université Paris-Sud - Paris 11 [UP11]
Samaille, Thomas [Auteur]
Sorbonne Université [SU]
Thiery, Nathalie [Auteur]
CHU Bordeaux
Dufouil, Carole [Auteur]
Université de Bordeaux [UB]
CHU Bordeaux
Delmaire, Christine [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Dormont, Didier [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Sorbonne Université [SU]
Chupin, Marie [Auteur]
Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM]
Sorbonne Université [SU]
Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM]
Sorbonne Université [SU]
De Rochefort, Ludovic [Auteur]
Université Paris-Sud - Paris 11 [UP11]
Samaille, Thomas [Auteur]
Sorbonne Université [SU]
Thiery, Nathalie [Auteur]
CHU Bordeaux
Dufouil, Carole [Auteur]
Université de Bordeaux [UB]
CHU Bordeaux
Delmaire, Christine [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Dormont, Didier [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Sorbonne Université [SU]
Chupin, Marie [Auteur]
Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM]
Sorbonne Université [SU]
Titre de la revue :
NeuroImage
Nom court de la revue :
Neuroimage
Numéro :
104
Pagination :
287-300
Date de publication :
2015-01-01
ISSN :
1053-8119
Mot(s)-clé(s) en anglais :
Susceptibility
Calcification
2D multislice
Phase processing
Harmonic filter
Microbleeds
Calcification
2D multislice
Phase processing
Harmonic filter
Microbleeds
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Cerebral microbleeds (CMBs) have emerged as a new imaging marker of small vessel disease. Composed of hemosiderin, CMBs are paramagnetic and can be detected with MRI sequences sensitive to magnetic susceptibility (typically, ...
Lire la suite >Cerebral microbleeds (CMBs) have emerged as a new imaging marker of small vessel disease. Composed of hemosiderin, CMBs are paramagnetic and can be detected with MRI sequences sensitive to magnetic susceptibility (typically, gradient recalled echo T2* weighted images). Nevertheless, their identification remains challenging on T2* magnitude images because of confounding structures and lesions. In this context, T2* phase image may play a key role in better characterizing CMBs because of its direct relationship with local magnetic field variations due to magnetic susceptibility difference. To address this issue, susceptibility-based imaging techniques were proposed, such as Susceptibility Weighted Imaging (SWI) and Quantitative Susceptibility Mapping (QSM). But these techniques have not yet been validated for 2D clinical data in multicenter settings. Here, we introduce 2DHF, a fast 2D phase processing technique embedding both unwrapping and harmonic filtering designed for data acquired in 2D, even with slice-to-slice inconsistencies. This method results in internal field maps which reveal local field details due to magnetic inhomogeneity within the region of interest only. This technique is based on the physical properties of the induced magnetic field and should yield consistent results. A synthetic phantom was created for numerical simulations. It simulates paramagnetic and diamagnetic lesions within a 'brain-like' tissue, within a background. The method was evaluated on both this synthetic phantom and multicenter 2D datasets acquired in standardized clinical setting, and compared with two state-of-the-art methods. It proved to yield consistent results on synthetic images and to be applicable and robust on patient data. As a proof-of-concept, we finally illustrate that it is possible to find a magnetic signature of CMBs and CMCs on internal field maps generated with 2DHF on 2D clinical datasets that give consistent results with CT-scans in a subsample of 10 subjects acquired with both modalities.Lire moins >
Lire la suite >Cerebral microbleeds (CMBs) have emerged as a new imaging marker of small vessel disease. Composed of hemosiderin, CMBs are paramagnetic and can be detected with MRI sequences sensitive to magnetic susceptibility (typically, gradient recalled echo T2* weighted images). Nevertheless, their identification remains challenging on T2* magnitude images because of confounding structures and lesions. In this context, T2* phase image may play a key role in better characterizing CMBs because of its direct relationship with local magnetic field variations due to magnetic susceptibility difference. To address this issue, susceptibility-based imaging techniques were proposed, such as Susceptibility Weighted Imaging (SWI) and Quantitative Susceptibility Mapping (QSM). But these techniques have not yet been validated for 2D clinical data in multicenter settings. Here, we introduce 2DHF, a fast 2D phase processing technique embedding both unwrapping and harmonic filtering designed for data acquired in 2D, even with slice-to-slice inconsistencies. This method results in internal field maps which reveal local field details due to magnetic inhomogeneity within the region of interest only. This technique is based on the physical properties of the induced magnetic field and should yield consistent results. A synthetic phantom was created for numerical simulations. It simulates paramagnetic and diamagnetic lesions within a 'brain-like' tissue, within a background. The method was evaluated on both this synthetic phantom and multicenter 2D datasets acquired in standardized clinical setting, and compared with two state-of-the-art methods. It proved to yield consistent results on synthetic images and to be applicable and robust on patient data. As a proof-of-concept, we finally illustrate that it is possible to find a magnetic signature of CMBs and CMCs on internal field maps generated with 2DHF on 2D clinical datasets that give consistent results with CT-scans in a subsample of 10 subjects acquired with both modalities.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Équipe(s) de recherche :
Troubles cognitifs dégénératifs et vasculaires
Date de dépôt :
2019-11-27T13:33:34Z
2020-03-03T10:18:10Z
2020-03-03T10:30:32Z
2020-03-03T10:18:10Z
2020-03-03T10:30:32Z