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Superficial temporal artery-middle cerebral ...
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Document type :
Article dans une revue scientifique: Article original
DOI :
10.1016/j.neuchi.2019.05.001
PMID :
31185229
Permalink :
http://hdl.handle.net/20.500.12210/16166
Title :
Superficial temporal artery-middle cerebral artery anastomosis patency correlates with cerebrovascular reserve in adult moyamoya syndrome patients
Author(s) :
Aboukais, Rabih [Auteur]
Verbraeken, Barbara [Auteur]
Leclerc, Xavier [Auteur] refId
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Gautier, Corinne [Auteur]
Henon, Hilde [Auteur] refId
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Vermandel, Maximilien [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Menovsky, Tomas [Auteur]
Lejeune, Jean-Paul [Auteur] refId
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Journal title :
Neuro-Chirurgie
Abbreviated title :
Neurochirurgie
Publication date :
2019-06-08
ISSN :
1773-0619
English keyword(s) :
Anastomosis
Brain perfusion
Cerebrovascular reserve
STA-MCA bypass
Moyamoya
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
OBJECTIVE: To evaluate the effectiveness of superficial temporal artery-middle cerebral artery (STA-MCA) bypass in improving cerebrovascular reserve (CVR) in Moyamoya syndrome. METHODS: This prospective study included 10 ...
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OBJECTIVE: To evaluate the effectiveness of superficial temporal artery-middle cerebral artery (STA-MCA) bypass in improving cerebrovascular reserve (CVR) in Moyamoya syndrome. METHODS: This prospective study included 10 consecutive patients treated for Moyamoya syndrome by STA-MCA bypass in our institution between June 2016 and January 2018. Perfusion MRI, transcranial Doppler and 99m Tc-HMPAO SPECT with acetazolamide challenge were performed before and after treatment to evaluate perfusion and cerebrovascular reserve. STA-MCA bypass was indicated for patients with history of ischemic or hemorrhagic stroke and when CVR was diminished on both transcranial Doppler and 99m Tc-HMPAO SPECT with acetazolamide challenge or brain perfusion was deteriorated on MRI. RESULTS: Bypass anastomosis was patent in all patients at end of surgery. One patient presented partial postoperative sensorimotor deficit related to an ischemic lesion in the frontal cortical area. One patient presented regressive chronic subdural hematoma without neurological deficit. Three months after treatment, CVR was significantly improved in 8 patients and unchanged in 2, probably related to low flow. Further follow-up found CVR deterioration in 1 patient, with anastomosis occlusion at 1 year. CONCLUSIONS: Our data suggest that improvement in cerebral perfusion and CVR depends on flow in the STA-MCA anastomosis in patients with Moyamoya syndrome. Systematic long-term follow-up of anastomosis flow, brain perfusion and CVR improves quantification of the benefit of STA-MCA anastomosis in terms of disease progression.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
Inserm
Université de Lille
Collections :
  • Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Submission date :
2019-11-27T13:34:18Z
Université de Lille

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