Brain metastases imaging
Document type :
Article dans une revue scientifique: Article original
PMID :
Permalink :
Title :
Brain metastases imaging
Author(s) :
Delmaire, Christine [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Savatovsky, J. [Auteur]
Boulanger, T. [Auteur]
Dhermain, F. [Auteur]
Le Rhun, Emilie [Auteur]
Metellus, P. [Auteur]
Gerber, S. [Auteur]
Carsin-Nicole, B. [Auteur]
Petyt, Gregory [Auteur]

Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Savatovsky, J. [Auteur]
Boulanger, T. [Auteur]
Dhermain, F. [Auteur]
Le Rhun, Emilie [Auteur]

Metellus, P. [Auteur]
Gerber, S. [Auteur]
Carsin-Nicole, B. [Auteur]
Petyt, Gregory [Auteur]
Journal title :
Cancer radiotherapie . journal de la Societe francaise de radiotherapie oncologique
Abbreviated title :
Cancer Radiother.
Volume number :
19
Pages :
16-19
Publication date :
2015-02-01
ISSN :
1278-3218
English keyword(s) :
MRI
MIBI
Nuclear medicine
Brain metastasis
PET
MIBI
Nuclear medicine
Brain metastasis
PET
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
The therapeutic management of brain metastases depends upon their diagnosis and characteristics. It is therefore imperative that imaging provides accurate diagnosis, identification, size and localization information of ...
Show more >The therapeutic management of brain metastases depends upon their diagnosis and characteristics. It is therefore imperative that imaging provides accurate diagnosis, identification, size and localization information of intracranial lesions in patients with presumed cerebral metastatic disease. MRI exhibits superior sensitivity to CT for small lesions identification and to evaluate their precise anatomical location. The CT-scan will be made only in case of MRI's contraindication or if MRI cannot be obtained in an acceptable delay for the management of the patient. In clinical practice, the radiologic metastasis evaluation is based on visual image analyses. Thus, a particular attention is paid to the imaging protocol with the aim to optimize the diagnosis of small lesions and to evaluate their evolution. The MRI protocol must include: 1) non-contrast T1, 2) diffusion, 3) T2* or susceptibility-weighted imaging, 4) dynamic susceptibility contrast perfusion, 5) FLAIR with contrast injection, 6) T1 with contrast injection preferentially using the 3D spin echo images. The role of the nuclear medicine imaging is still limited in the diagnosis of brain metastasis. The Tc-sestamibi brain imaging or PET with amino acid tracers can differentiate local brain metastasis recurrence from radionecrosis but still to be evaluated.Show less >
Show more >The therapeutic management of brain metastases depends upon their diagnosis and characteristics. It is therefore imperative that imaging provides accurate diagnosis, identification, size and localization information of intracranial lesions in patients with presumed cerebral metastatic disease. MRI exhibits superior sensitivity to CT for small lesions identification and to evaluate their precise anatomical location. The CT-scan will be made only in case of MRI's contraindication or if MRI cannot be obtained in an acceptable delay for the management of the patient. In clinical practice, the radiologic metastasis evaluation is based on visual image analyses. Thus, a particular attention is paid to the imaging protocol with the aim to optimize the diagnosis of small lesions and to evaluate their evolution. The MRI protocol must include: 1) non-contrast T1, 2) diffusion, 3) T2* or susceptibility-weighted imaging, 4) dynamic susceptibility contrast perfusion, 5) FLAIR with contrast injection, 6) T1 with contrast injection preferentially using the 3D spin echo images. The role of the nuclear medicine imaging is still limited in the diagnosis of brain metastasis. The Tc-sestamibi brain imaging or PET with amino acid tracers can differentiate local brain metastasis recurrence from radionecrosis but still to be evaluated.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
INSERM
Inserm
Université de Lille
CNRS
INSERM
Inserm
Université de Lille
Submission date :
2019-11-27T13:34:24Z