Title :

Quantitative multi-slice computed tomography assessment of the mitral valvular complex for transcatheter mitral valve interventions part 1: systematic measurement methodology and inter-observer variability

Author(s) :

Theriault-Lauzier, Pascal [Auteur]
Mylotte, Darren [Auteur]
Dorfmeister, Magdalena [Auteur]
Spaziano, Marco [Auteur]
Andalib, Ali [Auteur]
Mamane, Samuel [Auteur]
Chetrit, Michael [Auteur]
Blanke, Philipp [Auteur]
Cecere, Renzo [Auteur]
Buithieu, Jean [Auteur]
Martucci, Giuseppe [Auteur]
Tchetche, Didier [Auteur]
Modine, Thomas [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Van Mieghem, Nicolas M. [Auteur]
Lange, Rudiger [Auteur]
Windecker, Stephan [Auteur]
Bilodeau, Luc [Auteur]
Leipsic, Jonathon [Auteur]
Piazza, Nicolo [Auteur]

Journal title :

EuroIntervention . journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Abbreviated title :

EuroIntervention

Volume number :

12

Pages :

E1011-E1020

Publication date :

2016-10-01

ISSN :

1774-024X

English keyword(s) :

multi-slice computed tomography
congestive heart failure
transcatheter heart valve
transcatheter mitral valve replacement
mitral regurgitation

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

OBJECTIVE: Transcatheter mitral valve replacement (TMVR) is an emerging technology with the potential to treat patients with severe mitral regurgitation at excessive risk for surgical mitral valve surgery. Multimodality ...
Show more >OBJECTIVE: Transcatheter mitral valve replacement (TMVR) is an emerging technology with the potential to treat patients with severe mitral regurgitation at excessive risk for surgical mitral valve surgery. Multimodality imaging of the mitral valvular complex and surrounding structures will be an important component for patient selection for TMVR. Our aim was to describe and evaluate a systematic multi-slice computed tomography (MSCT) image analysis methodology that provides measurements relevant for transcatheter mitral valve replacement. RESULTS: A systematic step-by-step measurement methodology is described for structures of the mitral valvular complex including: the mitral valve annulus, left ventricle, left atrium, papillary muscles and left ventricular outflow tract. To evaluate reproducibility, two observers applied this methodology to a retrospective series of 49 cardiac MSCT scans in patients with heart failure and significant mitral regurgitation. For each of 25 geometrical metrics, we evaluated inter-observer difference and intra-class correlation. The inter-observer difference was below 10% and the intra-class correlation was above 0.81 for measurements of critical importance in the sizing of TMVR devices: the mitral valve annulus diameters, area, perimeter, the inter-trigone distance, and the aorto-mitral angle. CONCLUSIONS: MSCT can provide measurements that are important for patient selection and sizing of TMVR devices. These measurements have excellent inter-observer reproducibility in patients with functional mitral regurgitation.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires

Submission date :

2019-11-27T14:29:33Z