Titre :

Cause of preterm birth as a prognostic factor for mortality

Auteur(s) :

Delorme, Pierre [Auteur]
Goffinet, François [Auteur]
Ancel, Pierre-Yves [Auteur]
Foix-L'helias, Laurence [Auteur]
Langer, Bruno [Auteur]
Lebeaux, Cécile [Auteur]
Marchand-Martin, Laetitia [Auteur]
Zeitlin, Jennifer [Auteur]
Ego, Anne [Auteur]
Arnaud, Catherine [Auteur]
Vayssiere, Christophe [Auteur]
Lorthe, Elsa [Auteur]
Durrmeyer, Xavier [Auteur]
Sentilhes, Loic [Auteur]
Subtil, Damien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Debillon, Thierry [Auteur]
Winer, Norbert [Auteur]
Kaminski, Monique [Auteur]
D'ercole, Claude [Auteur]
Dreyfus, Michel [Auteur]
Carbonne, Bruno [Auteur]
Kayem, Gilles [Auteur]

Titre de la revue :

Obstetrics and gynecology

Nom court de la revue :

Obstet. Gynecol.

Numéro :

127

Pagination :

40-48

Date de publication :

2016-01-01

ISSN :

0029-7844

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

OBJECTIVE: To investigate the association of the cause of preterm birth on in-hospital mortality of preterm neonates born from 24 to 34 weeks of gestation. METHODS: L'Etude épidémiologique sur les petits âges gestationnels ...
Lire la suite >OBJECTIVE: To investigate the association of the cause of preterm birth on in-hospital mortality of preterm neonates born from 24 to 34 weeks of gestation. METHODS: L'Etude épidémiologique sur les petits âges gestationnels (EPIPAGE)-2 is a prospective, nationwide, population-based cohort of very preterm births. After dividing causes of preterm birth into six mutually exclusive groups, we analyzed the association of each cause with in-hospital deaths of preterm neonates born alive with adjustment for organizational, maternal, and obstetric factors. RESULTS: The analysis included 3,138 singleton live births from 24 to 34 weeks of gestation with a newborn in-hospital mortality rate of 5.0% (95% confidence interval 4.5-5.7). Preterm labor was the most frequent cause of preterm birth (n=1,293 [43.5%]) followed by preterm premature rupture of membranes (n=765 [23.9%]), hypertensive disorders without suspected fetal growth restriction (n=397 [12.7%]), hypertensive disorders with suspected fetal growth restriction (n=408 [10.9%]), placental abruption after an uncomplicated pregnancy (n=92 [3.0%]), and suspected fetal growth restriction without hypertensive disorders (n=183 [5.9%]). Neonates born because of suspected fetal growth restriction with or without hypertensive disorders (adjusted odds ratio [OR] 3.0 [1.9-4.7] and adjusted OR 2.3 [1.1-4.6], respectively) had higher adjusted risks of in-hospital death than those born after preterm labor. Risks of in-hospital mortality for preterm births caused by preterm premature rupture of membranes (adjusted OR 1.3 [0.9-1.9]), hypertensive disorders without fetal growth restriction (adjusted OR 0.7 [0.4-1.4]), or placental abruption (adjusted OR 1.6 [0.7-3.7]) were similar to those born after preterm labor. CONCLUSIONS: Among neonates born alive before 34 weeks of gestation, only those born because of suspected fetal growth restriction have a higher mortality risk than those born after preterm labor.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2019-12-09T16:53:15Z